泌尿器科領域の出血に対するAC-17使用経験

Abstract

A new intravenouslya dministeredh emostaticc al l e dA C-17(a drenochromeder ivative)i s utilized in this clinical study. This material is soluble in water, hence it is not necessary to be prepared by using sodium salicylate as a solubilizing agent. The patient was given 10 mg of AC-17 intramuscularly or intravenously every eight to twelve hours, and some cases were given postoperatively5 % glucose solution containing3 0-50m g of AC-17in travenously. This drug was used pre- and postoperatively in 61 cases of urological surgery (16 cases of nephrectomy1, 6 cases of retropubic prostatectomy, 8 cases of nephrolithotomy andt he others), and bleedingi n operationa nd postoperativeh ematuria are inhibited Nine patients of so-callede ssential hematuria were treated with AC-1 7 a, nd in 4 cases hematuriad isappeared.