所謂特発性腎出血に関する研究 第IV篇:本症例の臨床的並びに摘出腎の病理組織学的研究

Abstract

In twelve patients in whom the cause of unilateral renal bleeding remained obscure after urological exminations nephrectomy was performed because of all other methods of treatment had failed. Histological examination of the removed kidneys showed the results as follows. 1) Following review of the pathological material in 12 cases, in 5 of these it became apparent that certain findings were common to all of them. The lesion consits of the massive deposit of calcium, localized remarkable congestion, dilatation of collecting tubules in some papillae and in some cases minute calculi adherent to these papillae. It can be said that marked stagnation in the renal papillae which may be caused by massive deposit of calcium must be one of the etiological factors in this disease, and the onset of hematuria is provocated by the desquamation of these calcium plaques. 2) Exact examination on other 7 cases revealed the several causes of renal bleeding such as localized interstitial nephritis 2, early lesion of benign papilloma in the renal pelvis 2, cavernous hemangioma in the renal papilla 1, allergic inflammation 1 and chronic follicular pyelitis 1