腎結核に於ける血液電解質の研究

Abstract

Electrolytes in the blood were measured to detect the disturbance of kidney function and to estimate its relationship to the severity of the disease and at the same time the ohanges in the concentrations of potassium and sodium in serum and urine under the state of sodium load were also investigated in eight patients with cutaneous ureterostomy for the survived tuberculous kidney and 53 patients with unilateral renal tuberculosis. 1) Preoperative potassium concentration in serum was increased i n patients with renal tuberculosis. This is more likely to be related to the severity of the disease and less likely to function of the kidney. 2) Sodium concentration i n serum in preoperative through postoperative period ranged within normal limit and this is less likely to be related to either the severity of the disease or function of the kindney. 3) Calcium concentratio n in serum in preoperative through postoperative period also ranged within normal limit and this is less likely to be related to either the severity of the disease or function of the kidney. 4) The higher the damage of kidney function, the lower the chloride concentration in serum and this is less likely to be related to the severity of the disease. 5) Preoperative increase in potassium concentration in serum s u ggested the destruction of the renal tissue and decrease in chloride concentration suggested the disturbance of tubular function. 6) Preo p erative sodium load resulted in slight increase in sodium concentration in serum and significant increase in sodium concentration in urine. Postoperative sodium load resulted in moderate and slight increase in sodium concentrations in serum and urine, respectively. This will probably be due to disappearance of disturbance of kidney function which has been resulted in loss of sodium. 7) Sodium load resulted in slight decre a se in potassium concentration in serum in both pre- and post-operative periods. Potassium concentration in urine was increased by sodium load in preoperative period and was significantly increased in postoperative period. This will probably suggest a transfer of potassium out of the cell due to an increase in sodium concentration within the cell and a recovery of function of the kidney.