泌尿器科領域に於けるFatgenの使用経験

Abstract

Parenteral administration of Fatgen in amount of 100-800 c c . was carried out on 21 patients during postoperative period in association with other fluid therapy. Fatgen was appraised as follows. 1) Untow a rd effect of Fatgen was found only in one case (4.7%) in which case the effect was not as severe as to terminate administration of Fatgen. Fatgen was considered to be safe parenteral fat derivative. 2) Untoward effect of Fatgen on peripheral blood picture, blood protein, electrolytes, hepatic and renal functions was not observed. Other parenteral fluids, such as banked blood, glucose and synthetic amino acid derivatives can be safely, continuously, and simultaneously administered. Therefore, in the field of urology since Fatgen can be safely administered without consideration of electrolyte balance in the patients with renal dysfunction or electrolyte unbalance providing taking account of fluid balance, it is useful not only in the postoperative patients but in the patients with acute renal insufficiency. 3) The average reduction of body weight, 3.23 kg, in the control group of postoperative patients was compared with that of the group to which fatgen was administration, whose reduction of body weight was only average 1.92 kg. The reduction of the latter was only 60 per cent of the control group. 4) Satisfactory parenteral nutriti v e fluid is presently available as far as carbohydrate and protein are concerned and safe parenteral fat has long been expected. It seemed more likely that Fatgen gained wide clinical trust in the surgical fields.