慈大式人工腎臓 "Jikei ELECTRO-DIALYZER"の研究 第4報: 基礎的諸問題

Abstract

The auther performed experiments to study v arious fundamental problems to improve the Jikei electro-dialyzer to give it higher efficiency and perfect safety. The results are summarized as follows : 1) In electrodialysis of the electrolytes, the anions are filtrated to the anode side and the cations to the cathode side. The urea is filtrated to either side of the electrodes, but somewhat more to the cathode side. 2) In order to study efficiency of th e Jikei Electro-dialyzer, the auther measured half crest value time of the salicilic acid and the urea nitrogen of the circulating fluid. It showed that the strength of the electric current gives the most important effect on the efficiency of the dialysis, and the width of the blood chamber, on the other hand, hardly gives any effect on it. Also, in the occasions when the filter membrane is unboiled, the filtrating temperature is low, the filtrating dimensions are small or the volume of the rinsing fluid is in small amount, the efficiency of dialysis is lowered only in a small grade without giving any considerable changes. 3) Upon comparing the half crest v a lue time of the various substances, the electrolytes show much higher filtrating velocity than the nonelectrolytes. 4) In the early models of the Jikei Electro-dialyz e r, the blood chamber was frequently polluted by the chlor gas which was eventually developed at the anode. In the latest model, however, this is successfully prevented by placing a cellophane membrane in the rinsing fluid chamber between electrode and blood chamber. Thus we can expect satisfactory safety in performing dialysis with Jikei Electrodialyzer Model-C.