副交感神経亢進剤ベサコリンの泌尿器科的応用

Abstract

The following clinical observations have been mad e on the use of parasympathomimetic agent, Besacolin (Bethanechol Chloride). 1) Besacolin in a dose of 2 .5 mg was injected to 19 patients with acute postoperative urinary retention and micturition was obtained in 43.4 per cent. 2) Oral administration of Besacolin powder three to f o ur times daily in a dose of 10 mg each to 11 patients with bladder dysfunction, such as hypotonic bladder and atonic bladder resulted in disappearance or decrease in residual urine in 7 cases, unknown course in 3 cases, and discontinuation of administration of the drug in 1 case because of its side effect. 3) It has been found by means of cystometry that intravesical pressure has risen and it has approximated to normal range in the patients with hypotonic and atonic bladder after administration of Besacolin. 4) Side effects enc o untered were uncomfortable feeling in the chest in 2 cases by Besacolin injection and nausea in 1 case by Besacolin powder.