続発性陰茎腫瘍を伴った前立腺癌の1例

Abstract

A 65-year-old man was first seen to the Kyoto Univers i t y Hospital on August 22, 1958, with the chief complaints of dysuria, urinary frequency and painful erection for 2 months. Examination disclosed two firm, indurated, irregular masses in the penile shaft. Rectal examination revealed findings suggestive of carcinoma of the prostate, which was confirmed by perineal needle biopsy. On October 3, 1958, the primary prostatic carcinoma was treated by interstitial injection of radioactive colloidal chromic phosphate (Cr'2PO4) through the combined retropubic-suprapubic approach according to Flocks' method, and a biopsy taken from the penile mass revealed metastatic adenocarcinoma distributed in small islets throughout the corporal bodies. Following this procedurs estrogen therapy was initiated, but the penile masses appeared to increase in size and turned to be ulcerative in type. On February 5, 1959, palliative penile amputation was done but he became progres sively worse and expired on April 16, 1959 which was 7 months following admission. Postmortem examination revealed metastatic carcinoma involving the base of the bladder as well as metastases to pelvic parietes, retroperitoneal space, the liver and the periosteum of right tibia.