泌尿器科領域におけるBSP肝クリアランス法(Goodman)の研究

Abstract

The BSP liver clearance (Goodman1 952)h as be e n characterized by quantitative assessment of hepatic function. In an attemp t to research for the fine hepatic disturbances caused by urinary tract diseases, the author examined the hepatic functions of patients with various urogenital disorders using the BSP clearance method, Takata reaction and cobalt reaction. In the group of patients with carcinoma of bladder and progressed p rostatic hypertrophy, it was found the disturbances of liver function were the most significant, but in the group of patients with renal and ureteral calculosis, hepatic function had been kept almost intact. Especially, these facts were clearly shown by BSP clearance method. Additionally, the studies were made on the operated patie n ts. As a result of this examination, the following conclusion was obtained. The prostatectomy brings the beneficial influences upon the injured hepatic functions. The estimated pfasma volume w h ich had been calculated by BSP clearance test showed maximum value in renal and ureteral calculosis group, but application of the "t" test showed that mean values of both groups were no different each other (p<0.05).