線維素溶解現象及び低線維素原血症を伴った前立腺癌の1例

Abstract

A case of prostatic cancer with hemorrhagic diathesis i s reported. In this case, excessive fibrinolytic activity and decrease in fibrinogen were proved by laboratory examinations. It is co n sidered that these findings are caused by a release of tissue activator or fibrinolysokinase from the cancer tissue into the blood stream resulting in the manifestation of the hemorrhagic symptomes. The hemorrhagic diathesis was improved by administration of Epsilon-aminocaproic acid, Stilbestrol and blood transfusions. Abdominal total prostatectomy with orchiectomy was successfully performed without excessive bleeding. Mechanism of the occurrence of hemorrhag i c diathesis due to fibrinolysis in cascs of nrostatic cancer was discussed.