泌尿器科領域における総腎及び分担腎クリアランスの臨床的研究 第1篇: 泌尿器科手術前後に於ける総腎及び分担腎クリアランスに関する研究

Abstract

Pre- and postoperative total renal clearance was estim a ted in 160 cases and separated renal clearance in 50 cases in which pyelo- or ureterolithotomy, nephrectomy, prostatectomy and partial cystectomy were performed. A few nonsurgical conditions were included. 1) The average level of pre- and postoperative clearances was found to b e significantly lower than normal. 2) Tota l renal clearance does not indicate exact renal function in urological diseases. 3) As to the effect of aging, both CPAH and CSTS were markedly lowered af t e r fourty years of age. 4) In t ravenous pyelography occasionally reflects better renal function than real one. 5) After pyelo- or ureterolithotomy CPAH rose on the affected side, however, re m ained unchanged or slightly decreased on the healthy side. CSTS elevated on both sides. 6) After nephrectomy compensatory function of solitary kidney was we l l demonstrated with CPAH and CSTS. Functionally compensation of the solitary kidney acquired after 41 of age was much less than those younger than 40 years old. 7) CPAH and CSTS were markedly elevated im m ediately after nephrectomy but they became gradually reduced as being 80-90% of normal value, after 6, -8 weeks. 8) No compensatory change of the solitary kidney after nephrecto m y was noted when its function had been originally reduced to below 50%.