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タイトル: | 核酸前駆物質AICA orotate(AICAMIN)による男性不妊の治療 |
その他のタイトル: | Aica Orotate, a Nucleic Acid Precursor, in the Treatment of Male Sterility |
著者: | 森, 昭 原, 信二 西垣, 定雄 長久, 謹三 |
著者名の別形: | MORI, Akira HARA, Shinji NISHIGAKI, Sadao CHOKYU, Kinzo |
キーワード: | Imidazoles Infertility, Male Nucleic Acids Orotic Acid STERILITY, MALE |
発行日: | Aug-1963 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 9 |
号: | 8 |
開始ページ: | 460 |
終了ページ: | 465 |
抄録: | AICA orotate (AICAMIN), a nucleic acid precursor, was u sed for the treatment of male sterility. Therapy with AICAMIN in doses of 600 mg/day administered orally was carried out for 4-10 weeks. 1. Of 10 cases of oligozoospermia, 6 showed an increase in sperm counts and 4 were irresponsive to the treatment. Sperm motility was slightly improved in 6 cases. 2. In all 4 cases of azoospermia treated, spermia did not appear in the seminal fluid. 3. Of the 4 cases of necrozoospermia and asthenozoospermia, 1 showed a m oderate increase in motility of the sperm and 3 were irresponsive to the treatment. 4. Five cases of oligozoospermia were treated with a com bination of AICAMIN and gonadotropic hormone preparations. The result was that the number of the sperm increased in all cases. The effect of this agent was remarkable especially in 2 cases. 5. No changes were observed in urinary 17-KS, urinary gonadotropin , and plasma cholesterol values before and after the administration of AICAMIN. |
URI: | http://hdl.handle.net/2433/112457 |
PubMed ID: | 14051178 |
出現コレクション: | Vol.9 No.8 |
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