前立腺分泌液に関する研究 ：各種ホルモン影響下に於ける前立腺分泌液の酸フォスファターゼについての実験的研究

Abstract

Effects of administration of various hormones on the a ctivity of the acid phosphatase of the prostatic fluid was studied in dog. The results of experiments are su m merized as follows. 1) Measurement of the acid phosphatase activi t y of the prostatic fluid was performed by means of Kind-King's method and Fishman-Lerner's method. The normal range was found to be between 272 and 648 K.A.U. 2) With administration of m ale hormones, the acid phosphatase activity increased more than twice as much as the control values, but the increases were not proportional to the dose of hormones administered. 3) With administr a tion of combined dose of the male and female hormones, the acid phosphatase activity showed a decrease with subsequent plateau at the lowered level. 4. A marked increase in the acid phosphatase activity was demonstrate d following administration of the gonadotropic hormone. 5) A slight increase was obser v ed following administration of prolactin. 6) ACTH administration made the acid phosphatase activity to be increased while cortisone administration showed no noticeable change. 7) In the thyroid hormone treated group , a slight decrease in the acid phosphatase activity was demonstrated.