ヒト精液酸性ホスファターゼに関する研究 2: ヒト血清中に存在する精液酸性ホスファターゼの阻害物質について

Abstract

A substance in rabbit serum which inhibited the a cid phosphatase activity present in human semen was reported in the first paper. In order to study an influence of the human serum upon the homogenous acid phosphatase in semen, an attempt of this experiment was made. S u bsequent result showed that human serum had a strong inhibition for the acid phosphatase in human semen, and this substance was dialysable and heat-stable and its action was not lost even by calcination. It was recognized that this substance belonged to cation from its adsorption on ion exchange column, and that Cu+ produced by Cu++ and the reductive substance in serum displayed the inhibition of the enzymatic activity.