前立腺分泌液のクエン酸代謝

Abstract

Determination of citric acid in prostatic fluid of dog was made under influences of various hormones. The results are summerized as follows. 1) The contents of citric acid in prostatic fluid of normal dog ranged between 0.875 and 1.569 mg/d1 with an average of 1, 143 mg/dl. 2) An increase was observed during administration of male sexual hormone. 3) With administration of female sexual hormone, a rapid decrea se was seen on the fifth day of treatment, and it was not returned to the pre-treatment level even at 15 days after sensation of administration. 4) With adminis tration of gonadotropic hormones, the maximum response in increasing citric acid was found on 7 th day of HCG treatment which showed greater effect than that of treatment with PMS. 5) With admi nistration of prolactin, the highest content of citric acid was demonstrated on 10th day of treatment. Although the increase was not prominent, effect of prolaction to the prostatic gland was apparently evident. 6) A slight increase in citric acid was observed with administration of ACTH, adrenocortical hormones and anabolic hormones. 7) No change of citric acid conten t was seen with administration of thyroid powder and salivary gland hormones.