泌尿器科領域に於けるウイントマイロン(Nalidixic acid)の使用経験

Abstract

Wintomyloni s one of a new series of recently sy n thesized 1.8-naphtyridine derivatives as antibacterial properties. A short clini c al trial was done in 30 patients with 31 infecting urinary organisms. The daily dose of Wintomylon was 3 gms. dividing 3 times and it was given for 5 to 22 days. Clinical cure was obtained in 25 out of the 30 patients. Twenty-five patient s with cystitis without associated pathology were cured with good effects especially. The toxic reactions in 30 patients treated with the drug were nau sea in two, epigastralgia and stomach fullness in one, nausea and stomach fullness in one, retract feeling of tongue in one, and brightness in one. Wintomylons eems to b e a safe and effective drug in urinary tract infections, especially those associated with E. coli.