Tetrahydroxyduinoneの泌尿器科的応用 1: 使用適応及び症例について

Abstract

Tetrahydroxyquinone, an oral drug for keloid, was administered to a total of 151 cases, including 8 patients with urinary tract tuberculosis, 37 post-operative patients who had been conservatory operated on various urinary tract diseases, 104 patients with bladder neck contracture and 2 patients with retroperitoneal fibrosis. The drug was proved to be 1) applicable as an alternative choice of adrenocortical hormone with chemotherapeutics for tuberculosis in which the hormone is indicated to be used, 2) expectable to have better results as supported therapy of operation or as single administration for pathologic lesions in which marked localized proliferation of fibrous tissue is taken place. Cases have been presented in detail where the use of the drug was quite beneficial. In only 1 case, side effects such as nausea and vomiting were observed which made the drug discontinued. Other cases were tolerated well even after a prolonged use for around 1 year without any significant changes in blood cells and blood chemistry.