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タイトル: | 糖尿病と男子性腺機能に関する研究 |
その他のタイトル: | Studies on diabetes mellitus and functions of the male sexual glands |
著者: | 長久, 謹三 ![]() |
著者名の別形: | CHOKYU, Kinzo |
キーワード: | Adult Diabetes Complications Erectile Dysfunction/diagnosis/etiology Humans Male Middle Aged Testis/physiopathology |
発行日: | Sep-1965 |
出版者: | 京都大学医学部泌尿器科学教室 |
誌名: | 泌尿器科紀要 |
巻: | 11 |
号: | 9 |
開始ページ: | 850 |
終了ページ: | 876 |
抄録: | The purpose of the study is to clarify the nature of f unctional disturbance of the sexual glands which often accompanied to male patients with diabetes mellitus. Out of 134 patients who were inquirely examined on their sexual functions, 78 patients (58.2%) were found to have impotence. As various endocrine function studies, urinary total 17-KS and its fractions, urinary 17-OHCS, urinary estrogens and their fractions, and urinary gonadotrophin were determ ined. The impressive results in patients with impotence due to diabetes mellitus were marked decreases in III, IV and V fractions of 17-KS and lowered urinary gonadotrophin. A part of patients was performed gonadotrophin test and semi n al vesicle absorption studies as the functional evaluation of the sexual glands. Histological examinations of the testicle obtain e d by biopsy performed in 18 patients showed atrophic pictures in 14 cases (77.8%). The main findings are summarized as 1) peritubular fibrosis 2) disturbance of spermatogenesis and 3) changes of interstitial blood vessels. Ou t of 12 cases, in which analysis of semen was performed, decisions of subfertility and infertility were made in 5 and 2 cases respectively. Concentration of fructose and total reducing substances in the semen was also determined. As the pathogenetic mechanisms of impotence in patient with diabetes mellitus , such theories as a specific status of hypogonadotrophic hypogonadism , occurrence of erectile impotence due to diabetic neuropathy and many other opinions have been elucidated. The author suggests multiglandular endocrine disorder theory in addition to the above theories . After all, it is supposed that the cause of impotence is by no means a single factor in diabetes mellitus which consists of very complicated multi-factors . |
URI: | http://hdl.handle.net/2433/112818 |
PubMed ID: | 5893358 |
出現コレクション: | Vol.11 No.9 |
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