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dc.contributor.author | 渡辺, 昌美 | ja |
dc.contributor.author | 川村, 俊三 | ja |
dc.contributor.author | 石崎, 充 | ja |
dc.contributor.alternative | WATANABE, Masami | en |
dc.contributor.alternative | KAWAMURA, Shunzo | en |
dc.contributor.alternative | ISHIZAKI, Mitsuru | en |
dc.date.accessioned | 2010-05-24T03:18:28Z | - |
dc.date.available | 2010-05-24T03:18:28Z | - |
dc.date.issued | 1967-02 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/113096 | - |
dc.description.abstract | Methacolimycin (each capsel contains 100 mg strength, 3 mil l i on units of colistin methanesulfonate sodium) was orally administered in order to determine its blood and urine concentrations. Then the drug was given to 26 patients with urinary tract infections to evatuate the clinical effectiveness. The results are summarized as follows. 1) The urinary concentration of this drug in patie n ts having normal renal function was the highest during 2 to 3 hours after oral administration and it decreased after 6 hours. In patients with renal function disturbance, however, the urinary concentration was lower than in patients with normal renal function although a sufficiently high blood concentration was achieved. 2) Among 26 cases given Methacolimycin, marked improvements of subjective symptoms and objective findings were noted in 12 cases. In addition other 7 cases showed some responses, so that a total of 19 cases was proved to be effective. In general, the effectiveness was less pronounced in cases with organic urinary tract changes than without changes. As the relation to the causal organisms, the drug was proved to have a relatively high effectiveness against E. coli and Proteus mirabilis while it had less effect against Staph. aureus and Stanh. enidermidis. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 京都大学医学部泌尿器科学教室 | ja |
dc.publisher.alternative | Department of Urology, Faculty of Medicine, Kyoto Univeersity | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Colistin/blood/therapeutic use/urine | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Urinary Tract Infections/drug therapy | en |
dc.subject.ndc | 494.9 | - |
dc.title | 尿路感染症に対するメタコリマイシンの使用経験 | ja |
dc.title.alternative | Use of methacolimycin for urinary tract infections | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 13 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 175 | - |
dc.identifier.epage | 181 | - |
dc.textversion | publisher | - |
dc.sortkey | 09 | - |
dc.address | 東北大学医学部泌尿器科学教室 | ja |
dc.address | 東北大学医学部泌尿器科学教室 | ja |
dc.address | 東北大学医学部泌尿器科学教室 | ja |
dc.address.alternative | the Department of Urology, Toholzu University Faculty of Medicine, Sendai | en |
dc.address.alternative | the Department of Urology, Toholzu University Faculty of Medicine, Sendai | en |
dc.address.alternative | the Department of Urology, Toholzu University Faculty of Medicine, Sendai | en |
dc.identifier.pmid | 5624107 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.13 No.2 |
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