性早熟症を伴った副腎癌の1例

Abstract

A 4 years old boy came to the hospital with chief com p laints of obesity, excess pelage, pubic hairing and hypertrophy of the penis. He was found to have blood pressure 152/94 mmHg and bone age 12 years. On pyelography, the right kidney was compressed specifically by a tumor mass which is the characteristic picture of adrenal tumor. Urinary 17 KS excretion was 132.32 mg per day and it was not suppressed by cortisone loading. In addition, various urinary steroid hormones showed marked increase in their excretion. Exploratory laparotomy confirmed that the tumor originated from the right adrenal gland and extensively infiltrated to the inner and inferior directions which made an extirpation of the tumor to be impossible. Histological examination revealed adenocarcinoma of the right adrenal gland.