泌尿器科領域におけるProctase Pの臨床経験

Abstract

As clinical application of "Proctase P", a total of 48 patients, who visited or entered in the Department of Urology of Hiroshima University Hospital and were considered to have indication, were administered the drug. The results obtained are summarized as follows. 1) Among 8 patients with cystitis given the drug with combination of antibiotics, the treatment was markedly effective in 3, effective in 3 and ineffective in 2, respectively. 2) The drug was effective in both of 2 patients with urethritis. 3) The drug was effective in 2 out of 5 patients with pyelonephritis. 4) A patient with orchitis due to mumps showed good response to the drug. 5) A case of tuberculous epididymitis with induration showed no response to the drug. 6) The drug was given to 8 patients performed genito-urinary operations, consisting of 2 for epididymectomia, 2 for plastic operation for hypospadias and 4 for phimosis, and it was effective for anti-edematous and anti-inflammatory purposes in 6 cases. 7) Among 8 patients operated on laparotomy for urinary tract diseases and had development of hematoma or excessive purulent discharge, administration of the drug was markedly effective in 2 and effective in 4 cases, respectively. 8) During post-operative indwelling catheter of prostatectomy, the drug was given after disapperance of hematuria. In 4 patients treated, 2 had marked effect and the other 2 had some effect. 9) In 12 patients performed bouginage, composed of 2 with post-prostatectomy urethral stricture, 1 with bladder neck sclerosis, 1 with prostatic hypertrophy, 5 with traumatic urethral stricture and 3 with post-gonorrheal urethral stricture, the drug was administered for the purpose of anti-edematous and anti-inflammatory means for urethral edema. It was markedly effective in 3 and effective in 4 cases, respectively. The over-all results of the treatment with "Proctase P" in 48 patients with urological diseases were markedly effective in 10, effective in 24 and ineffective in 14 cases, respectively, with the effective rate being 70.8 %. As the side effects, 3 patients, 6.2 % of all cases, complained of anorexia or epigastric fullness. No patient showed skin eruptions, stomatitis or bleeding tendency.