Extra-adrenal pheochromocytoma (paraganglioma) of the urinary bladder : a case report

Abstract

49歳男性.患者は肉眼的血尿を主訴に来院となった.所見では, 持続する高血圧や排尿後の高血圧は認められなかったものの, 膀胱鏡にて腫瘍が認められ, 経尿道的膀胱腫瘍切除術を施行した.切除標本の病理診断は傍神経節腫であった.尚, 血中のカテコラミンはほぼ正常範囲内であり, 経尿道的膀胱腫瘍切除術中に高血圧発作を起こすことはなく, 非機能性の傍神経節腫であった.術後5ヵ月経過現在, 再発を認められていない

The case of a 49-year-old male patient with paraganglioma of the urinary bladder is presented here. The patient's only complaint was of gross hematuria: sustained hypertension and post-micturitional hypertension were not presented. Transurethral resection was performed to diagnose the bladder tumor. Pathological examination resulted in the diagnosis that the resected tissue was a paraganglioma. Computed tomography, magnetic resonance imaging and iodine-131-labeled metaiodbenzylguanidine scintigraphy revealed that the tumor was a primary paraganglioma in the urinary bladder. Plasma concentrations of the catecholamines were virtually within the normal limits. Hypertensive crisis was not revealed during the transurethral resection. The tumor was non-functional. Partial cystectomy was performed. The patient has remained disease-free for five months after surgery.