A case of lupus cystitis diagnosed from urinary symptoms as the sole initial complaint

Abstract

37歳女性.患者は重度の膀胱刺激症状のみを主訴とし受診, 膀胱生検で粘膜下の炎症と血管炎の所見を認めた.血液データより自己免疫疾患が疑われたため, 更に検査を追加したところSLE(全身性エリテマトーデス)およびループス膀胱炎と診断された.治療として早期のステロイド投与を行なったところ重度の膀胱刺激症状は軽快した

Cystitis related with systemic lupus erythematosis (SLE) is termed as lupus cystitis. It is a subtype of SLE in which gastrointestinal and bladder symptoms are prominent and it usually manifests with other symptoms of SLE. We present a case in a 37-year-old woman whose sole complaint was the severe urinary symptoms. A biopsy of the bladder showed inflammation in the submucosa and the finding of vasculitis. An autoimmune disease was suspected from the blood serum sample. A further laboratory study was performed and she was diagnosed with SLE and lupus cystitis. Prompt therapy with corticosteroids resulted in the improvement of the severe bladder symptoms.