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DCフィールド | 値 | 言語 |
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dc.contributor.author | Uchida, Toyoaki | en |
dc.contributor.author | Baba, Shiro | en |
dc.contributor.author | Irie, Akira | en |
dc.contributor.author | Soh, Shigehiro | en |
dc.contributor.author | Masumori, Naoya | en |
dc.contributor.author | Tsukamoto, Taiji | en |
dc.contributor.author | Nakatsu, Hiroomi | en |
dc.contributor.author | Fujimoto, Hiroyuki | en |
dc.contributor.author | Kakizoe, Tadao | en |
dc.contributor.author | Ueda, Takeshi | en |
dc.contributor.author | Ichikawa, Tomohiko | en |
dc.contributor.author | Ohta, Nobutaka | en |
dc.contributor.author | Kitamura, Tadaichi | en |
dc.contributor.author | Sumitomo, Makoto | en |
dc.contributor.author | Hayakawa, Masamichi | en |
dc.contributor.author | Aoyagi, Teiichiro | en |
dc.contributor.author | Tachibana, Masaaki | en |
dc.contributor.author | Ikeda, Ryusuke | en |
dc.contributor.author | Suzuki, Kohji | en |
dc.contributor.author | Tsuru, Nobuo | en |
dc.contributor.author | Suzuki, Kazuo | en |
dc.contributor.author | Ozono, Seiichiro | en |
dc.contributor.author | Fujimoto, Kiyohide | en |
dc.contributor.author | Hirao, Yoshihiko | en |
dc.contributor.author | Monden, Kohichi | en |
dc.contributor.author | Nasu, Yasutomo | en |
dc.contributor.author | Kumon, Hiromi | en |
dc.contributor.author | Nishi, Kazuhiko | en |
dc.contributor.author | Ueda, Shoichi | en |
dc.contributor.author | Koga, Hirofumi | en |
dc.contributor.author | Naitoh, Seiji | en |
dc.contributor.alternative | 内田, 豊昭 | ja |
dc.contributor.alternative | 馬場, 志郎 | ja |
dc.contributor.alternative | 入江, 啓 | ja |
dc.contributor.alternative | 宋, 成浩 | ja |
dc.contributor.alternative | 舛森, 直哉 | ja |
dc.contributor.alternative | 塚本, 泰司 | ja |
dc.contributor.alternative | 中津, 裕臣 | ja |
dc.contributor.alternative | 藤元, 博行 | ja |
dc.contributor.alternative | 垣添, 忠生 | ja |
dc.contributor.alternative | 植田, 健 | ja |
dc.contributor.alternative | 市川, 智彦 | ja |
dc.contributor.alternative | 太田, 信隆 | ja |
dc.contributor.alternative | 北村, 唯一 | ja |
dc.contributor.alternative | 住友, 誠 | ja |
dc.contributor.alternative | 早川, 正道 | ja |
dc.contributor.alternative | 青柳, 貞一郎 | ja |
dc.contributor.alternative | 橘, 政昭 | ja |
dc.contributor.alternative | 池田, 龍介 | ja |
dc.contributor.alternative | 鈴木, 孝治 | ja |
dc.contributor.alternative | 鶴, 信雄 | ja |
dc.contributor.alternative | 鈴木, 和雄 | ja |
dc.contributor.alternative | 大園, 誠一郎 | ja |
dc.contributor.alternative | 藤本, 清秀 | ja |
dc.contributor.alternative | 平尾, 佳彦 | ja |
dc.contributor.alternative | 門田, 晃一 | ja |
dc.contributor.alternative | 那須, 保友 | ja |
dc.contributor.alternative | 公文, 裕巳 | ja |
dc.contributor.alternative | 西, 一彦 | ja |
dc.contributor.alternative | 上田, 昭一 | ja |
dc.contributor.alternative | 古賀, 寛史 | ja |
dc.contributor.alternative | 内藤, 誠二 | ja |
dc.date.accessioned | 2010-05-25T08:11:09Z | - |
dc.date.available | 2010-05-25T08:11:09Z | - |
dc.date.issued | 2005-10 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/113709 | - |
dc.description.abstract | 限局性前立腺癌に対する高密度焦点式超音波療法の多施設共同研究の成績について報告した.対象は, stageT1-2N0M0の72例の限局性前立腺癌で, 症例の年齢中央値は72歳, 血清PSA中央値は8.10n/mlであった.その結果, 治療効果は全体では1年78%, 2年76%が非再発生存であった.浸潤度別に2年目の生化学的非再発生存率を集計したところ, stage T1cが89%, stage T2a 67%, stage T2bは40%(p=0.0817)であった.悪性度別では, Gleason 2~4群は88%, Gleason 5~7群は72%, Gleason 8~10群は80%(p=0.6539)であった.術前の血清PSA値別2年非再発生存率は, PSAが10ng/ml以下群は75%, 10~20ng/ml群は78%(p=0.6152)であった.術後6ヵ月目の前立腺生検では68%において癌細胞は認められなかった.前立腺体積は, 術前24.2mlから術後6ヵ月目14.0mlと縮小していた(p<0.01).IPSS, 最大尿流量率, Functional Assessment of Cancer Therapy(FACT)を用いた生活の質項目は術前後に有意な変化は認められなかった.以上, 高密度焦点式超音波療法は, 術前血清PSA値が20ng/ml以下の限局性前立腺癌に対して低侵襲性でかつ有用な治療法だと思われた | ja |
dc.description.abstract | We report a multicenter trial with transrectal high-intensity focused ultrasound (HIFU) in the treatment of localized prostate cancer. A total of 72 consecutive patients with stage T1c-2NOM0 prostate cancer were treated using the Sonablate 500TM HIFU device (Focus Surgery, Indianapolis, USA). Biochemical recurrence was defined according to the criteria recommended by the American Society for Therapeutic Radiology and Oncology Consensus Panel. The median age and prostate specific antigen (PSA) level were 72 years and 8.10 ng/ml, respectively. The median follow-up period for all patients was 14.0 months. Biochemical disease-free survival rates in all patients at 1 and 2 years were 78% and 76%, respectively. Biochemical disease-free survival rates in patients with stage T1c, T2a and T2b groups at 2 years were 89, 67% and 40% (p = 0.0817). Biochemical disease-free survival rates in patients with Gleason scores of 2-4, 5-7 and 8-10 at 2 years were 88, 72% and 80% (p = 0.6539). Biochemical disease-free survival rates in patients with serum PSA of less than 10 ng/ml and 10-20 ng/ml were 75% and 78% (p = 0.6152). No viable tumor cells were noted in 68% of patients by postoperative prostate needle biopsy. Prostatic volume was decreased from 24.2 ml to 14.0 ml at 6 months after HIFU (p < 0.01). No statistically significant differences were noted in International Prostate Symptom Score, maximum urinary flow rate and quality of life analysis with Functional Assessment of Cancer Therapy. HIFU therapy appears to be minimally invasive, efficacious and safe for patients with localized prostate cancer with pretreatment PSA levels less than 20 ng/ml. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Prostate cancer | en |
dc.subject | High-intensity focused ultrasound | en |
dc.subject | Minimally invasive surgery | en |
dc.subject.ndc | 494.9 | - |
dc.title | Transrectal high-intensity focused ultrasound in the treatment of localized prostate cancer : a multicenter study | en |
dc.title.alternative | 限局性前立腺癌に対する高密度焦点式超音波療法:多施設共同研究 | ja |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 51 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 651 | - |
dc.identifier.epage | 658 | - |
dc.textversion | publisher | - |
dc.sortkey | 02 | - |
dc.address | The Department of Urology, Tokai University Hachioji Hospital | en |
dc.address | The Department of Urology, Kitasato University | en |
dc.address | The Department of Urology, Sapporo Medical University | en |
dc.address | The Department of Urology, Asahi General Hospital | en |
dc.address | The Department of Urology, National Cancer Center | en |
dc.address | The Department of Urology, Chiba University | en |
dc.address | The Department of Urology, Tokyo University | en |
dc.address | The Department of Urology, National Defense Medical College | en |
dc.address | The Department of Urology, Tokyo Medical University | en |
dc.address | The Department of Urology, Kanazawa Medical University | en |
dc.address | The Department of Urology, Hamamatsu University School of Medicine | en |
dc.address | The Department of Urology, Nara Medical University | en |
dc.address | The Department of Urology, Okayama University | en |
dc.address | The Department of Urology, Kumamoto University | en |
dc.address | The Department of Urology, Kyusyu University | en |
dc.address.alternative | 東海大学八王子病院泌尿器科 | ja |
dc.address.alternative | 北里大学医学部泌尿器科 | ja |
dc.address.alternative | 札幌医科大学泌尿器科 | ja |
dc.address.alternative | 旭中央病院泌尿器科 | ja |
dc.address.alternative | 国立がんセンター泌尿器科 | ja |
dc.address.alternative | 千葉大学医学部泌尿器科 | ja |
dc.address.alternative | 東京大学医学部泌尿器科 | ja |
dc.address.alternative | 防衛医科大学泌尿器科 | ja |
dc.address.alternative | 東京医科大学泌尿器科 | ja |
dc.address.alternative | 金沢医科大学医学部泌尿器科 | ja |
dc.address.alternative | 浜松医科大学医学部泌尿器科 | ja |
dc.address.alternative | 奈良県立医科大学医学部泌尿器科 | ja |
dc.address.alternative | 岡山大学医学部泌尿器科 | ja |
dc.address.alternative | 熊本大学医学部泌尿器科 | ja |
dc.address.alternative | 九州大学医学部泌尿器科 | ja |
dc.identifier.pmid | 16285617 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.51 No.10 |
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