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Title: 膀胱癌と前立腺癌の病期画像診断の進歩 : Endorectal MRI and MTC
Other Titles: The progress in diagnostic imaging for staging of bladder and prostate cancer: endorectal magnetic resonance imaging and magnetization transfer contrast
Authors: 有馬, 公伸  KAKEN_name
林, 宣男  KAKEN_name
柳川, 眞  KAKEN_name
川村, 壽一  KAKEN_name
小林, 茂樹  KAKEN_name
竹田, 寛  KAKEN_name
杉村, 芳樹  KAKEN_name
Author's alias: ARIMA, Kiminobu
Keywords: Endorectal MRI
Bladder cancer
Prostate cancer
Issue Date: Aug-1999
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 45
Issue: 8
Start page: 553
End page: 557
Abstract: 1)Endorectal MRIの有用性は,膀胱癌では病期診断,前立腺癌では精嚢腺浸潤の高い正診率で示された. 2)magnetization transfer contrastは,前立腺癌の局在診断に有用な検査法である
We retrospectively studied the staging accuracy of endorectal magnetic resonance imaging (MRI) in comparison with transrectal ultrasound examination (TRUS) for 71 localized bladder cancers and 19 localized prostate cancers (PC) radically resected. The accuracy of clinical staging for bladder cancer in endorectal MRI and TRUS was 85.9% and 69.2%, respectively. The presence or absence of the continuity of submucosal enhancement on T2-weighted MRI images could be useful for the staging of bladder cancer. The accuracy of the seminal vesicular invasion for prostate cancer in endorectal MRI and TRUS was 95% and 63%, respectively. To determine whether magnetization transfer contrast (MTC) provides additional information in the diagnosis of prostate cancer, the magnetization transfer ratios (MTRs) were calculated in 22 patients with PC, 5 with benign prostatic hyperplasia (BPH) and 4 controls. The mean MTR in the peripheral zone of the normal prostate (8.0% +/- 3.4 [standard deviation]) showed a statistically significant decrease relative to that in the inner zone of the normal prostate (27.4% +/- 3.4, p < 0.01), BPH (25.5% +/- 3.7, p < 0.01), pre-treatment PC (30.6% +/- 5.9, p < 0.01), and PC after hormonal therapy (20.3% +/- 6.3, p < 0.01). The mean MTR in pre-treatment PC was significantly higher than that in BPH, or in PC after hormonal therapy (p < 0.01). MTC was considered to be useful for conspicuity of prostate cancer lesion.
PubMed ID: 10500962
Appears in Collections:Vol.45 No.8

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