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Title: インターフェロンにより肺転移と肝転移が消失した腎細胞癌の1症例
Other Titles: Complete remission of lung and hepatic metastases from renal cell carcinoma by interferon alpha-2b therapy: a case report
Authors: 岡根谷, 利一  KAKEN_name
村田, 靖  KAKEN_name
杵渕, 芳明  KAKEN_name
Author's alias: OKANEYA, Toshikazu
MURATA, Yasushi
Keywords: Interferon a-2b
Renal cell carcinoma
Lung metastasis
Hepatic metastasis
Tumor thrombus
Issue Date: Sep-1999
Publisher: 泌尿器科紀要刊行会
Journal title: 泌尿器科紀要
Volume: 45
Issue: 9
Start page: 617
End page: 619
Abstract: 74歳男.肺転移と肝転移がインターフェロンα2bの投与後に消失し,その後も完全緩解を保っている
A right renal tumor was found in a 74-year-old man with multiple metastases to the lungs and liver. Tumor thrombus extending into the inferior vena cava and a right spermatic varicocele were also noted at the first visit. Interferon alpha-2b and interferon gamma were administered for treatment. Partial remission of lung metastases, complete remission of hepatic metastases, and disappearance of the varicocele occurred after 4, 6 and 8 weeks, respectively. Then the primary right renal tumor was resected. Although only interferon alpha-2b was continued twice weekly by self-injection, complete remission of the lung metastases was obtained 13 weeks after the initiation of therapy. No evidence of recurrence or new metastasis has been found after 18 months. These results indicate that even advanced renal cell carcinoma may show a rapid response to interferon alpha. Interferon alpha is worth trying for metastatic renal cell carcinoma and should be continued for at least a few months.
PubMed ID: 10540707
Appears in Collections:Vol.45 No.9

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