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タイトル: | インターフェロンにより肺転移と肝転移が消失した腎細胞癌の1症例 |
その他のタイトル: | Complete remission of lung and hepatic metastases from renal cell carcinoma by interferon alpha-2b therapy: a case report |
著者: | 岡根谷, 利一 村田, 靖 杵渕, 芳明 |
著者名の別形: | OKANEYA, Toshikazu MURATA, Yasushi KINEBUCHI, Yoshiaki |
キーワード: | Interferon a-2b Renal cell carcinoma Lung metastasis Hepatic metastasis Tumor thrombus |
発行日: | Sep-1999 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 45 |
号: | 9 |
開始ページ: | 617 |
終了ページ: | 619 |
抄録: | 74歳男.肺転移と肝転移がインターフェロンα2bの投与後に消失し, その後も完全緩解を保っている A right renal tumor was found in a 74-year-old man with multiple metastases to the lungs and liver. Tumor thrombus extending into the inferior vena cava and a right spermatic varicocele were also noted at the first visit. Interferon alpha-2b and interferon gamma were administered for treatment. Partial remission of lung metastases, complete remission of hepatic metastases, and disappearance of the varicocele occurred after 4, 6 and 8 weeks, respectively. Then the primary right renal tumor was resected. Although only interferon alpha-2b was continued twice weekly by self-injection, complete remission of the lung metastases was obtained 13 weeks after the initiation of therapy. No evidence of recurrence or new metastasis has been found after 18 months. These results indicate that even advanced renal cell carcinoma may show a rapid response to interferon alpha. Interferon alpha is worth trying for metastatic renal cell carcinoma and should be continued for at least a few months. |
URI: | http://hdl.handle.net/2433/114121 |
PubMed ID: | 10540707 |
出現コレクション: | Vol.45 No.9 |
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