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46_117.pdf | 5.67 MB | Adobe PDF | 見る/開く |
タイトル: | 腎盂絨毛癌の1例 |
その他のタイトル: | Choriocarcinoma of the renal pelvis: a case report |
著者: | 原, 智 伊藤, 敬一 長田, 浩彦 橘, 政昭 村井, 勝 秦, 順一 |
著者名の別形: | HARA, Satoshi ITO, Keiichi NAGATA, Hirohiko TACHIBANA, Masaaki MURAI, Masaru HATA, Junichi |
キーワード: | Renal pelvic tumor Choriocarcinoma hCG-/3 Chemotherapy |
発行日: | Feb-2000 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 46 |
号: | 2 |
開始ページ: | 117 |
終了ページ: | 121 |
抄録: | 68歳男, 絨毛癌への変異を伴った腎盂移行上皮癌を経験した.尿路上皮に発生した絨毛癌は予後不良とされているが, 本症においてはMVC療法及びそれに続くPEB療法が有効であり良好な成績を得た A 68-year-old male presented to our hospital complaining of gross hematuria. Intravenous pyelography subsequently demonstrated a left non-visualized kidney, and he was admitted for further evaluation. Cystoscopy revealed a bladder tumor around the left ureteral orifice and retrograde pyelography showed a filling defect in the left renal pelvis. The urinary cytology from the left renal pelvis indicated class IV, and the microscopic findings of a bladder biopsy demonstrated grade 1 transitional cell carcinoma. We performed transurethral resection of bladder tumor (TUR-BT) followed by left nephroureterectomy with bladder cuff. The pathological diagnosis was high grade transitional cell carcinoma with choriocarcinomatous component. After the operation, the serum human chorionic gonadotropin-beta (hCG-beta) level was slightly elevated, and the combination chemotherapy with methotrexate, vinblastine and cisplatin (MVC) was administered. Although the serum hCG-beta level fell to 0.1 ng/ml, after two courses of MVC chemotherapy, bilateral pulmonary metastases appeared in the chest X-ray with increasing hCG-beta levels. Salvage chemotherapy with cisplatin, etoposide and bleomycin (PEB) was performed. After two courses of PEB chemotherapy, the serum hCG-beta level fell to within the normal range and all pulmonary metastases disappeared. |
URI: | http://hdl.handle.net/2433/114215 |
PubMed ID: | 10769802 |
出現コレクション: | Vol.46 No.2 |
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