前立腺原発移行上皮癌の1例

Abstract

67歳男.排尿困難を主訴に他院を受診し, 移行上皮癌G3と診断され紹介入院となった.病理組織診断と, 多中心性尿路上皮性腫瘍の除外を目的とした経尿道的膀胱及び前立腺生検術を施行し, 前立腺原発移行上皮癌と診断した.ネオアジュバント療法としてM-VAC全身化学療法を施行し, 効果判定はNCであった.その後, 膀胱前立腺尿道摘除術, 骨盤リンパ節郭清術, 回腸導管造設術を施行した

A 67-year-old male was admitted with a three-month history of voiding difficulty. Prostate specific antigen remained within the normal limit. Under the diagnosis of benign prostatic hypertrophy, transurethral resection of prostate was performed. Pathological examination of the resected specimens of the prostate revealed transitional cell carcinoma. Two courses of systemic M-VAC (methotrexate, vinblastine, doxorubicin, cisplatin) chemotherapy were performed, followed by cystoprostatourethrectomy, pelvic lymphadenectomy, and ileal conduit construction. Now one year has elapsed, with no clinical signs of recurrence.