前立腺肥大症に対する経尿道的高温度療法の治療成績

Abstract

前立腺肥大症60例に対してプロストケアを使用した経尿道的高温度療法を施行し, 2ヵ月後に排尿障害臨床試験ガイドラインにしたがって効果判定を行った.1)I-PSS及びQOL indexは有意の改善を示した.2)最大尿流率及び平均尿流率は改善を示したが, 有意ではなかった.3)前立腺体積には有意の変化は認められなかった.4)全般治療効果ではやや有効以上は78%, 不変は22%であり, 患者満足度では大体満足以上73%, 不満足27%であった.5)副作用として, 2例に射精障害を認めた

The clinical efficacy of transurethral microwave thermotherapy using the PROSTCARE apparatus was evaluated in 60 patients with bladder outlet obstruction associated with benign prostatic hyperplasia. All of the 60 patients received a single thermal session for 60 minutes with an average intraprostatic temperature of 45 degrees C. They were evaluated by analyzing the international prostate symptom score (IPSS), quality of life (QOL) index, maximum urinary flow rate and prostate volume at 2 months after the treatment to estimate criteria for efficacy of treatment in BPH. Both IPSS and QOL index improved significantly. The maximum urinary flow rate improved but there was no significant change. There was no significant change in prostate volume. The rates of improvement in IPSS, QOL index and maximum flow rate were 73%, 78% and 47% of the patients respectively. The rate of overall improvement was 78% of the patients. As a complication after the treatment, 2 patients complained of ejaculation disturbance.