CA19-9-producing transitional cell carcinoma of the renal pelvis: a case report

Abstract

59歳の男性が水腎症により当科へ紹介になった.逆行性腎盂造影で左腎盂内に不整陰影欠損を認め, 分腎尿細胞診が陽性であった.左腎盂腫瘍と診断し左腎盂尿管全摘除術を施行, 病理診断は移行上皮癌で免疫組織学的に腫瘍内にCA19-9の局在を認めた.術前高値であった血清CA19-9が術後漸減, 正常化した.術後血清CA19-9の上昇ならびに腫瘍の再発を認めていない

We report a case of CA19-9-producing transitional cell carcinoma of the renal pelvis. A 59-year-old male patient with left hydronephrosis was referred to us from a local physician. Retrograde pyelogram revealed irregular filling defects involving calices, pelvis and proximal ureter. The serum CA19-9 level was elevated. Under the diagnosis of renal pelvic tumor, we performed radical left nephroureterectomy. The tumor was histologically diagnosed as transitional cell carcinoma. The tumor cells showed positive immunostaining for CA19-9. The serum CA19-9 level was normalized after the operation. To our knowledge, this is the 28th case of a CA19-9-producing tumor in the Japanese literature.