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dc.contributor.author | 福井, 義尚 | ja |
dc.contributor.author | 三馬, 省二 | ja |
dc.contributor.author | 藤本, 健 | ja |
dc.contributor.author | 明山, 達哉 | ja |
dc.contributor.author | 山口, 旭 | ja |
dc.contributor.author | 平山, 暁秀 | ja |
dc.contributor.alternative | FUKUI, Yoshihisa | en |
dc.contributor.alternative | SAMMA, Shoji | en |
dc.contributor.alternative | FUJIMOTO, Ken | en |
dc.contributor.alternative | AKIYAMA, Tatsuya | en |
dc.contributor.alternative | YAMAGUCHI, Akira | en |
dc.contributor.alternative | HIRAYAMA, Akihide | en |
dc.date.accessioned | 2010-05-27T07:00:59Z | - |
dc.date.available | 2010-05-27T07:00:59Z | - |
dc.date.issued | 2001-05 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/114528 | - |
dc.description.abstract | 今回の検討にて, 新しい膀胱癌の尿中マーカーであるNMP-22及びBTAの有用性が示された.MNP-22は診断前スクリーニングに優れているのに対して, BTAは治療後経過観察に優れている.膀胱鏡検査にこれらの検査と尿細胞診を組み合わせることにより, 非侵襲的に膀胱癌の診断率が高まることが期待される | ja |
dc.description.abstract | We evaluated the utility of urinary parameters (Nuclear Matrix Protein-22: NMP-22, Bladder Tumor Antigen: BTA, and cytological examinations) for the diagnosis or post-therapeutic monitoring of bladder cancer. Thirty one tumor-bearing cases including 19 fresh cases and 40 tumor-free cases, were subjects of this study. Using identical voided urine samples, NMP-22, BTA and urinary cytology were examined. The mean values of NMP-22 (cut-off value is 12 U/ml) was 100.5 +/- 26.5 U/ml in the tumor-bearing group and 21.9 +/- 7.8 U/ml in the tumor-free group (p < 0.05): Sensitivity was 74.2%, and specificity was 67.5%. Sensitivity of BTA was 58.1%, and specificity was 97.5%. Only five cases were judged positive by urinary cytology: 16.1% in sensitivity and 100% in specificity. Thus, NMP-22 and BTA were more sensitive than urinary cytology. In conclusion, the new urinary parameters, NMP-22 and BTA, would be less invasive and useful as tumor markers of bladder cancer. NMP-22 seems suitable for screening before the diagnosis and BTA for the post-therapeutic follow-up study. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Bladder cancer | en |
dc.subject | Tumor marker | en |
dc.subject | NMP-22 | en |
dc.subject | BTA | en |
dc.subject | Urinary cytology | en |
dc.subject.ndc | 494.9 | - |
dc.title | 膀胱癌診断におけるスクリーニング法の検討 : Nuclear matrix protein-22, Bladder tumor antigenならびに尿細胞診の比較 | ja |
dc.title.alternative | Screening methods in the detection of bladder cancer: comparison of nuclear matrix protein-22, bladder tumor antigen and cytological examinations | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 47 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 311 | - |
dc.identifier.epage | 314 | - |
dc.textversion | publisher | - |
dc.sortkey | 04 | - |
dc.address | 奈良県立奈良病院泌尿器科 | ja |
dc.address | 奈良県立奈良病院泌尿器科 | ja |
dc.address | 奈良県立奈良病院泌尿器科 | ja |
dc.address | 奈良県立奈良病院泌尿器科 | ja |
dc.address | 奈良県立奈良病院泌尿器科 | ja |
dc.address | 奈良県立奈良病院泌尿器科 | ja |
dc.address.alternative | the Department of Urology, Nara Prefectural Nara Hospital | en |
dc.address.alternative | the Department of Urology, Nara Prefectural Nara Hospital | en |
dc.address.alternative | the Department of Urology, Nara Prefectural Nara Hospital | en |
dc.address.alternative | the Department of Urology, Nara Prefectural Nara Hospital | en |
dc.address.alternative | the Department of Urology, Nara Prefectural Nara Hospital | en |
dc.address.alternative | the Department of Urology, Nara Prefectural Nara Hospital | en |
dc.identifier.pmid | 11433750 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.47 No.5 |
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