セルトリ細胞腫の1例

Abstract

24歳男.無痛性左陰嚢内腫瘤を主訴とした.外陰部は男性型で女性化乳房は認めなかった.エコーにより精巣内腫瘍を認め, 全身CTや骨シンチでは異常を認めなかった.左高位精巣摘除術を施行し, 病理組織診によりセルトリ細胞腫であると診断した.病理学的に良性腫瘍であると考えられたが, 経過観察は必要であると考えられる

A 24-year-old man was admitted to our hospital with the complaint of a painless mass in the left testis. Gynecomastia was not present. The serum levels of alpha fetoprotein and human chorionic gonadotropin-beta were not elevated. Ultrasound sonography showed a hypoechoic lesion in the left testis. There was no evidence of retroperitoneal lymph node enlargement or distant metastasis on computerized tomography. With a diagnosis of left testicular tumor, left high orchiectomy was done. The tumor measured 10 x 11 mm in size within the testis and was histologically diagnosed as benign Sertoli cell tumor. Immunohistochemcal analysis revealed negative findings with the tumor markers inhibin, CAM 5.2, pancytokeratin, EMA, and PLAP. No adjuvant therapy was performed. Twenty-six cases of Sertoli cell tumor of the testis in the Japanese literature are reviewed.