インポテンス症例における血管拡張剤の陰茎海綿体内自己注射法の臨床的検討 : 長期成績について

Abstract

1)9例のインポテンス患者に塩酸パパベリンを第一選択として陰茎海綿体内自己注射法を指導したところ, 自己注射が技術的に困難であった1例を除いた8例全例で挿入可能な完全勃起を認め, 性交可能となり本人およびパートナーの満足がえられた。2)1例で勃起機能が回復し治癒し, 射精は3例に認められた。なお, 観察期間中自己注射484回施行で副作用は認めなかった

From December 1989 to September 1992, nine patients with impotence were instructed to perform intracavernous self-injection of vasoactive drugs. At first 40 mg of papaverine hydrochloride was used in all patients and the response on erection was evaluated. If the response did not show sufficiently functional erection, a mixture of 40 mg of papaverine hydrochloride and 1 mg of phentolamine mesylate or 20 mg of prostaglandin E1 was reinjected. Eight patients had achieved full erections and vaginal penetrations without noteworthy complications during the follow-up period. Out of eight patients, three patients were able to ejaculate and one patient showed recovery of erection. No major side effects were seen. In conclusion, intracavernous self-injection is a useful modality for impotence.