泌尿器科領域における癌化学療法時の感染症の検討

Abstract

感染症の頻度や好発する感染症の種類を知るため発熱の原因を検討した。1)発熱の原因不明のものは26例中11例にみられた。発熱原因として腎盂腎炎が最も多くみられたが, 基礎疾患として水腎症の存在が重要と考えられた。2)発熱は末梢白血球数が2, 000/mm3以下の症例に多くみられた

To examine the frequency and the type of infection during cancer chemotherapy in the urological field, we studied the causes of fever in 67 patients with genitourinary cancer. Twenty-six patients had developed a fever of higher than 38 degrees C. Although fever without proven infection was seen in 11 patients (42.3%), fever caused by pyelonephritis was the most common infection. There was a relationship between fever and the presence of hydronephrosis. Fever was observed more often in patients with a leucocyte count of less than 2, 000 white blood cell/mm3. In conclusion, we recommend the interruption of cancer chemotherapy or the use of granulocyte colony-stimulating factor for the prevention of infection, when the leukocyte count is less than 2, 000 cell/mm3, especially in patients with hydronephrosis.