Kock回腸膀胱の組織学的変化を造設2年9ヵ月後剖検にて検討しえた1例

Abstract

62歳男, 回腸膀胱の粘膜組織像は光学顕微鏡で陰窩の数が減少し, 杯細胞数が増加していた。腎盂・尿管粘膜には特に異常を認めず, 回腸重積部にも虚血性変化等も認められなかった。さらにpouch壁に線維化や萎縮も認められず, 輸出脚部のcatheterizationによる明らかな損傷も認められなかった

A 62-year-old male patient consulted us because of gross hematuria and was diagnosed as having a bladder tumor. Total cystectomy was performed and a Koch pouch was utilized. Two years and nine months later, he died as a result of recurrence of bladder tumor and pathological autopsy was performed. A microscopic section of the reservoir mucosa showed a reduction in the number of crypts and an increase in the number of goblet cells. These morphological changes seemed to be caused by chronic exposure to urine, but have a favorable effect upon metabolic alterations following the utilization of the Kock pouch.