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DCフィールド | 値 | 言語 |
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dc.contributor.author | 有馬, 公伸 | ja |
dc.contributor.author | 柳川, 眞 | ja |
dc.contributor.author | 杉村, 芳樹 | ja |
dc.contributor.author | 栃木, 宏水 | ja |
dc.contributor.author | 川村, 寿一 | ja |
dc.contributor.author | 斎藤, 薫 | ja |
dc.contributor.author | 山崎, 義久 | ja |
dc.contributor.author | 森, 脩 | ja |
dc.contributor.author | 大本, 安一 | ja |
dc.contributor.author | 中川, 雅照 | ja |
dc.contributor.alternative | Arima, Kiminobu | en |
dc.contributor.alternative | Yanagawa, Makoto | en |
dc.contributor.alternative | Sugimura, Yoshiki | en |
dc.contributor.alternative | Tochigi, Hiromi | en |
dc.contributor.alternative | Kawamura, Juichi | en |
dc.contributor.alternative | Saitoh, Kaoru | en |
dc.contributor.alternative | Yamazaki, Yoshihisa | en |
dc.contributor.alternative | Mori, Osamu | en |
dc.contributor.alternative | Oomoto, Yasuichi | en |
dc.contributor.alternative | Nakagawa, Masateru | en |
dc.date.accessioned | 2010-05-28T05:08:24Z | - |
dc.date.available | 2010-05-28T05:08:24Z | - |
dc.date.issued | 1994-06 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/115295 | - |
dc.description.abstract | 対象は転移を有しIFN-αを投与した16名, 転移はなくIFN-αを投与した16名, 転移はなく, IFN-α非投与の25名の腎癌である。腎摘後およびIFN-α投与後にNK細胞比率は低下する傾向を認めた。IFN-α投与後, CD 4陽性細胞比率が有意に上昇を示し活性化CD 4陽性細胞比率とCD 4陽性細胞比率/CD 8陽性細胞比率はやや上昇傾向をみた。CD 8陽性細胞比率と活性化CD 8陽性細胞比率は特に変化を認めなかった。IFN-α投与とCD 4陽性細胞比率の変化の関連を認めた | ja |
dc.description.abstract | To study the changes in the subsets of peripheral blood lymphocytes before and after nephrectomy and interferon (IFN) therapy, 57 patients with renal cell carcinoma were divided into three groups; one group consisted of 16 patients with metastasis who had been administered IFN-alpha, one group consisted of 16 patients without metastasis who had been administered IFN-alpha, and the other consisted of 25 patients without metastasis who had not been administered IFN-alpha. Immunological parameters such as percentages of NK (Leu-11+ [Leu-7-) cells, percentages of activated CD4 (Leu-3a+ HLA-DR+) positive cells and percentages of activated CD8 (Leu-2a+ HLA-DR+) positive cells were examined by two color flow cytometry and the percentages of CD4 (Leu-3a+) positive cells, percentages of CD8 (Leu-2a+) positive cells values and the ratio of percentages of CD4 positive cells/percentages of CD8 positive cells were evaluated. The percentages of NK cells showed a tendency to decrease after nephrectomy and the administration of IFN-alpha. The percentage of CD4 positive cells showed a significant increase after the administration of IFN-alpha. The percentage of activated CD4 positive cells and the ratio of percentage of CD4 positive cells/percentage of CD8 positive cells showed a tendency to increase slightly. The percentage of CD8 positive cells and percentage of activated CD8 positive cells showed no particular changes. There was a specific correlation between the administration of IFN-alpha and the changes of percentage of CD4-positive cells and this suggests that the administration of IFN-alpha led to the increase of helper T cells. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Renal cell carcinoma | en |
dc.subject | Interferon-a | en |
dc.subject | PBL subset | en |
dc.subject | Nephrectomy | en |
dc.subject.ndc | 494.9 | - |
dc.title | 腎摘除術あるいはInterferon-α投与による腎癌患者の末梢血リンパ球サブセットの変動 | ja |
dc.title.alternative | Effects of nephrectomy and interferon administration on immunological parameters in patients with renal cell carcinoma | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 40 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 469 | - |
dc.identifier.epage | 474 | - |
dc.textversion | publisher | - |
dc.sortkey | 01 | - |
dc.address | 三重大学医学部泌尿器科学教室 | ja |
dc.address | 三重大学医学部泌尿器科学教室 | ja |
dc.address | 三重大学医学部泌尿器科学教室 | ja |
dc.address | 三重大学医学部泌尿器科学教室 | ja |
dc.address | 三重大学医学部泌尿器科学教室 | ja |
dc.address | 鈴鹿中央病院泌尿器科 | ja |
dc.address | 山本総合病院泌尿器科 | ja |
dc.address | 済生会松阪病院泌尿器科 | ja |
dc.address | 大塚細胞工学研究所 | ja |
dc.address | 大塚製薬応用開発部 | ja |
dc.address.alternative | the Department of Urology, Mie University School of Medicine | en |
dc.address.alternative | the Department of Urology, Mie University School of Medicine | en |
dc.address.alternative | the Department of Urology, Mie University School of Medicine | en |
dc.address.alternative | the Department of Urology, Mie University School of Medicine | en |
dc.address.alternative | the Department of Urology, Mie University School of Medicine | en |
dc.address.alternative | the Department of Urology, Suzuka Chuou Hospital | en |
dc.address.alternative | the Department of Urology, Yamamoto Sougou Hospital | en |
dc.address.alternative | the Department of Urology, Saiseikai Matsuzaka Hospital | en |
dc.address.alternative | Otsuka Pharmaceutical Co., L T D Cellular Technology Institute | en |
dc.address.alternative | Otsuka Pharmaceutical Co., L T D Product Application Development Dept. | en |
dc.identifier.pmid | 8073952 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.40 No.6 |
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