続発性前立腺悪性リンパ腫の1例

Abstract

排尿困難を主訴とした72歳男で, 前立腺肥大症と診断し, 経尿道的前立腺摘除術を行った.切除材料の40%の診断は悪性リンパ腫であった.免疫組織化学的にLSG分類上, B細胞起源の瀰漫性, 中細胞型で, B細胞性非ホジキンリンパ腫と診断した.3クールの複合化学療法を行った.終了時点の前立腺生検では, 悪性リンパ腫の細胞は認められなかった

A 72-year-old man presenting with difficulty of urination, was diagnosed with benign prostatic hyperplasia and transurethral resection of prostate (TUR-P) was performed. However, pathological diagnosis of 40% of the TUR-specimen was of malignant lymphoma. Immunohistochemical examination revealed B-cell origin, diffuse and medium-cell type, according to the LSG classification. Then we performed chemotherapy with a combination of cyclophosphamide, adriamycin, vincristine and prednisolone. Trans-rectal biopsy specimens of the prostate after 3 courses of chemotherapy, revealed no cells of malignant lymphoma.