前立腺肥大症に対する経尿道的バルーンレーザー高温度療法の治療成績

Abstract

53例を対象に, 自覚症状, 他覚所見, 前立腺推定体積の改善度及び有効率を術前後で検討した.自覚症状は有意かつ著明な改善を認めたが, 他覚所見としてのurodynamic parameterは改善を認めなかった.また, 前立腺推定体積の縮小は認めなかった

Between April 1994 and March 1995, transurethral balloon laser thermotherapy (TUBAL-T) using Prostalase was performed on 53 patients with benign prostatic hyperplasia. Clinical efficacy was evaluated at 3 months after TUBAL-T. The mean international prostate symptom score (I-PSS) decreased from 21.5 at baseline to 11.3 after 3 months (p < 0.0001). Irritative (the sum of items 1, 2, 4 and 7 of I-PSS) decreased by 55%, while obstructive symptoms (the sum of items 3, 5 and 6 of I-PSS) by 45%. However, other objective parameters such as maximum flow rate, voided volume, percent postvoid residual volume and prostate volume showed no significant change (7.8 to 7.2 ml/s, 130 to 147 ml, 33 to 28% and 39.7 to 41.0 ml, respectively). In conclusion, significant improvement after TUBAL-T was observed for subjective symptoms, especially irritative symptoms, but not for objective parameters.