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| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| 43_829.pdf | 332.53 kB | Adobe PDF | 見る/開く |
| タイトル: | 前立腺癌遺伝子治療の臨床応用への検討 |
| その他のタイトル: | Clinical application for gene therapy in prostate cancer |
| 著者: | 後藤, 章暢  守殿, 貞夫 CHUNG, Leland W. K. |
| 著者名の別形: | GOTOH, Akinobu KAMIDONO, Sadao CHUNG, Leland W. K. |
| キーワード: | Gene therapy Prostate cancer Adenovirus TK Tumor suppressor gene |
| 発行日: | Nov-1997 |
| 出版者: | 泌尿器科紀要刊行会 |
| 誌名: | 泌尿器科紀要 |
| 巻: | 43 |
| 号: | 11 |
| 開始ページ: | 829 |
| 終了ページ: | 833 |
| 抄録: | Prostate cancer;Progression model;Gene therapy;Osteocalcin promoter;PSA promoter Hormone treatment, radiotherapy and anti-cancer chemotherapy are often used to treat prostate cancer. However, there is no effective method of treating hormone-independent prostate cancer. In this study, we attempted to establish a new treatment method for hormone-independent prostate cancer. We developed a new recombinant adenovirus vector containing a suicide gene and controlled by a tissue specific promoter, and examined the usefulness of gene therapy for hormone-independence and PSA expression in prostate cancer. We have also examined the usefulness of gene therapy involving an adenovirus and various tumor suppressor genes for human prostate cancer cells, which are under trial in the United States. |
| URI: | http://hdl.handle.net/2433/116060 |
| PubMed ID: | 9436031 |
| 出現コレクション: | Vol.43 No.11 |
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