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タイトル: | PSA値Gray zoneにおける前立腺癌の診断 : Free及びTotal PSAの有用性 |
その他のタイトル: | Free/total ratio of prostate-specific antigen (PSA) for prostate cancer detection in patients with gray zone PSA level |
著者: | 田中, 方士 村上, 信乃 五十嵐, 辰男 阿部, 拓 鈴木, 孝一 関田, 信之 島崎, 淳 |
著者名の別形: | TANAKA, Masashi MURAKAMI, Shino IGARASHI, Tatsuo ABE, Taku SUZUKI, Koichi SEKITA, Nobuyuki SHIMAZAKI, Jun |
キーワード: | Prostate cancer F/T ratio Free PSA Gray zone |
発行日: | Dec-1997 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 43 |
号: | 12 |
開始ページ: | 855 |
終了ページ: | 860 |
抄録: | Thirty seven patients complaining of voiding disturbance who showed gray zone total prostate-specific antigen (t-PSA) level (upper limit of normal approximately 10 ng/ml) but did not reveal apparent cancerous findings in the prostate were examined for free PSA (f-PSA) and prostate volume. According to histological diagnosis, 9 were cancer cases and the other 28 were non-cancer cases. The free/total (F/T) ratio was 0.10 and 0.16 in the cancer and non-cancer groups, respectively (t-PSA; DPC kit, p = 0.03). The t-PSA (DPC and Dinabott kits), f-PSA and PSA density alone did not distinguish these two groups. For diagnosis of cancer, the ratio seemed to be F/T, the most reliable followed by PSA density and t-PSA. When using a 13% F/T, the sensitivity and specificity for cancer detection were 88.9 and 70.8%, respectively. t-PSA measured with the Dinabott kit, showed a similar tendency except that the F/T ratio showed a slight variation. Prostate volume and patient age influenced the F/T slightly, but these factors may not impair the usefulness of F/T. |
URI: | http://hdl.handle.net/2433/116092 |
PubMed ID: | 9488932 |
出現コレクション: | Vol.43 No.12 |
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