東葛病院におけるProstate specific antigen(PSA)単独前立腺癌検診の試行 : 経過観察脱落者の検討

Abstract

前立腺検査受診者550人中前立腺癌患者は11人であった.PSA高値で経過観察必要群として翌年PSA測定を試みたが測定し得たのは47人中33人であった.経過観察できなかった14人の理由では現在困っていないが8人で最も多かった.QOLスコアは, 経過観察可能群では2.6±1.6, 経過観察不能群では1.7±1.0, I-PSS合計点数は経過観察可能群では11.3±7.1, 経過観察不能群では6.0±4.1であった

We studied the usefulness of prostate cancer screening using prostate specific antigen (PSA) and PSA density (PSAD). In the first year of this screening (1995), we detected prostate cancer in 11 out of 550 (1.7%) subjects. Only 33 of the 47 (70%) subjects whose PSA values were greater than the cut-off value could be followed the following year. The remaining 14 subjects could not be followed mainly because of absence of urination difficulty at that time. The international prostate symptom score (I-PSS) sum and the quality of life (QOL) score at the screening in the unfollowed group were significantly lower than those in the followed group. The subjects who must be followed and whose QOL score and I-PSS sum are low at the time of screening need more careful and persuasive explanation from the urologist on the importance of long-term follow-up.