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タイトル: | Molecular forms of serum prostate-specific antigen: the clinical usefulness of percent free PSA to discriminate prostate cancer from BPH |
その他のタイトル: | 血清前立腺特異抗原(PSA)の分子型 : 前立腺癌をBPHから鑑別する遊離PSA百分率の臨床的有用性 |
著者: | ABRAHAMSSON, Per-Anders KURIYAMA, Manabu |
キーワード: | PSA PSA molecular form F/T Prostate cancer Screening |
発行日: | Apr-1998 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 44 |
号: | 4 |
開始ページ: | 223 |
終了ページ: | 232 |
抄録: | The development of increasingly specific diagnostic assays has allowed the detection of various forms of prostate-specific antigen (PSA). It has been found that the proportion of free to total PSA (percent free PSA) is significantly lower in men with prostate cancer than in those with other benign diseases. In order to distinguish early, curable prostate cancer from benign prostatic hyperplasia (BPH), percent free PSA measurement is most useful when the total PSA value is 3-10 ng/ml. The measurement of the proportions of these different forms of PSA, i.e., percent free PSA, may constitute an important diagnostic tool, able to differentiate between benign and malignant prostatic disease with increased specificity, reducing false-positive results and, therefore, improve patient prognosis. |
URI: | http://hdl.handle.net/2433/116168 |
PubMed ID: | 9617617 |
出現コレクション: | Vol.44 No.4 |
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