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dc.contributor.author今井, 強一ja
dc.contributor.author山中, 英壽ja
dc.contributor.author久保田, 裕ja
dc.contributor.author三木, 誠ja
dc.contributor.author伊藤, 貴章ja
dc.contributor.author赤座, 英之ja
dc.contributor.author内田, 克紀ja
dc.contributor.author頴川, 晋ja
dc.contributor.author栗山, 学ja
dc.contributor.author渡邉, 泱ja
dc.contributor.author沖原, 宏治ja
dc.contributor.author古武, 敏彦ja
dc.contributor.author宇佐美, 道之ja
dc.contributor.author荒井, 陽一ja
dc.contributor.author前田, 浩ja
dc.contributor.author鷺山, 和幸ja
dc.contributor.author齊藤, 泰ja
dc.contributor.author酒井, 英樹ja
dc.contributor.author志田, 圭三ja
dc.contributor.alternativeIMAI, Kyoichien
dc.contributor.alternativeYAMANAKA, Hidetoshien
dc.contributor.alternativeKUBOTA, Yutakaen
dc.contributor.alternativeMIKI, Makotoen
dc.contributor.alternativeITO, Takaakien
dc.contributor.alternativeAKAZA, Hideyukien
dc.contributor.alternativeUCHIDA, Katsunorien
dc.contributor.alternativeEGAWA, Shinen
dc.contributor.alternativeKURIYAMA, Manabuen
dc.contributor.alternativeWATANABE, Hirokien
dc.contributor.alternativeOKIHARA, Kojien
dc.contributor.alternativeKOTAKE, Toshihikoen
dc.contributor.alternativeUSAMI, Michiyukien
dc.contributor.alternativeARAI, Yoichien
dc.contributor.alternativeMAEDA, Hiroshien
dc.contributor.alternativeSAGIYAMA, Kazuyukien
dc.contributor.alternativeSAITO, Yutakaen
dc.contributor.alternativeSAKAI, Hidekien
dc.contributor.alternativeSHIDA, Keizoen
dc.date.accessioned2010-05-28T06:22:31Z-
dc.date.available2010-05-28T06:22:31Z-
dc.date.issued1998-10-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/116264-
dc.description.abstract1)f-PSAとc-PSA測定系とも各抗原を特異的に測定し, t-PSA測定系はf-PSAとc-PSAを1:1の割合で測定していた. 2)f/t%とf/c%は共にPCaにおいてA1やB0のような早い病期からnon PCaと有意差が認められた. 3)t-PSAとc-PSA及びf/t%とf/c%のROC曲線における差は殆ど認められず, c-PSAの診断上の有用性はt-PSAと同等と思われた.f-PSA単独では有用性が認められなかった. 4)t-PSAが4~10ng/mlの検体においてはf/t%とf/c%がPSA-Dと同様に前立腺癌の診断に有効であった. 5)前立腺体積40ml以上でt-PSAが10ng/ml以下では癌でない確率が高いja
dc.description.abstractWe studied the clinical significance of serum prostate specific antigen (PSA) ratio: free-PSA/total-PSA and free-PSA/complex-PSA to discriminate between prostate cancer (PC) and prostate benign disease (non-PCa) by using total-PSA, alpha 1-antichymotrypsin complexed (complex)-PSA and free-PSA enzyme-linked immunosorbent assay (ELISA) kits newly developed at EIKEN Chemical Co, Ltd. Fre-PSA and complex-PSA ELISA kits demonstrated high sensitivity and specificity. Total-PSA ELISA kit also demonstrated equimolarity for free-PSA and complex-PSA. On the total-PSA range of 4-10 ng/ml, free-PSA/total-PSA% (f/t%) and free-PSA/complex-PSA% (f/c%) were very useful to discriminate between PCa and non-PCa by receiver operating characteristic curve analysis as well as PSA density (PSA-D) but not free-PSA level. F/t% and f/c% were even useful to discriminate early stage PCa (i.e. A1 or B0) from non-PCa by the Mann-Whitney U-test.en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher泌尿器科紀要刊行会ja
dc.subjectProstate-specific antigenen
dc.subjectProstate canceren
dc.subjectfree PSAen
dc.subjectfree/total PSAen
dc.subjectE-PLATE EIKEN(R)PSAen
dc.subject.ndc494.9-
dc.titleEプレート'栄研' PSAキットを用いた臨床的検討 : 前立腺癌患者におけるfree PSA, complex PSA, およびfree/total%の臨床有用性ja
dc.title.alternativeClinical utility of the free prostate specific antigen (PSA), alpha 1-antichymotrypsin-complexed PSA, and free/total PSA ratio using the specific and sensitive enzyme-linked immunosorbent assay "E-plate EIKEN PSA"en
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume44-
dc.identifier.issue10-
dc.identifier.spage755-
dc.identifier.epage763-
dc.textversionpublisher-
dc.sortkey15-
dc.address熱川温泉病院泌尿器科ja
dc.address群馬大学医学部泌尿器科学教室ja
dc.address群馬大学医学部泌尿器科学教室ja
dc.address東京医科大学泌尿器科学教室ja
dc.address東京医科大学泌尿器科学教室ja
dc.address筑波大学臨床医学系泌尿器科学教室ja
dc.address筑波大学臨床医学系泌尿器科学教室ja
dc.address北里大学医学部泌尿器科学教室ja
dc.address岐阜大学医学部泌尿器科学教室ja
dc.address京都府立医科大学泌尿器科学教室ja
dc.address京都府立医科大学泌尿器科学教室ja
dc.address大阪府立成人病センター泌尿器科ja
dc.address大阪府立成人病センター泌尿器科ja
dc.address倉敷中央病院泌尿器科ja
dc.address倉敷中央病院泌尿器科ja
dc.address医療法人原三信病院泌尿器科ja
dc.address長崎大学医学部泌尿器科学教室ja
dc.address長崎大学医学部泌尿器科学教室ja
dc.address財団法人前立腺研究財団ja
dc.address.alternativeAtagawa Onsen Hospitalen
dc.address.alternativethe Department of Urology, Gunma University School of Medicineen
dc.address.alternativethe Department of Urology, Gunma University School of Medicineen
dc.address.alternativethe Department of Urology, Tokyo Medical Collegeen
dc.address.alternativethe Department of Urology, Tokyo Medical Collegeen
dc.address.alternativethe Department of Urology, Institute of Clinical Medicine, University of Tsukubaen
dc.address.alternativethe Department of Urology, Institute of Clinical Medicine, University of Tsukubaen
dc.address.alternativethe Department of Urology K, itasato University School of Medicineen
dc.address.alternativethe Department of Urology, Gifu University School of Medicineen
dc.address.alternativethe Department of Urology, Kyoto Prefectural University of Medicineen
dc.address.alternativethe Department of Urology, Kyoto Prefectural University of Medicineen
dc.address.alternativethe Department of Urology, Osaka Medical Centefror Cancerand Cardiovascular Diseasesen
dc.address.alternativethe Department of Urology, Osaka Medical Centefror Cancerand Cardiovascular Diseasesen
dc.address.alternativethe Department of Urology, Kurasiki- Central Hospitalen
dc.address.alternativethe Department of Urology, Kurasiki- Central Hospitalen
dc.address.alternativeHarasansin Hospitalen
dc.address.alternativethe Department of Urology, Nagasaki University School of Medicineen
dc.address.alternativethe Department of Urology, Nagasaki University School of Medicineen
dc.address.alternativeJapanese Foundation of Prostate Researchen
dc.identifier.pmid9850846-
dcterms.accessRightsopen access-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
出現コレクション:Vol.44 No.10

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