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dc.contributor.author岡村, 廉晴ja
dc.contributor.author橋本, 博ja
dc.contributor.author森川, 満ja
dc.contributor.author西原, 正幸ja
dc.contributor.author佐賀, 祐司ja
dc.contributor.author八竹, 直ja
dc.contributor.author小山内, 裕昭ja
dc.contributor.author山内, 薫ja
dc.contributor.alternativeOKAMURA, Kiyoharuen
dc.contributor.alternativeHASHIMOTO, Hiroshien
dc.contributor.alternativeMORIKAWA, Mitsuruen
dc.contributor.alternativeNISHIHARA, Masayukien
dc.contributor.alternativeSAGA, Yujien
dc.contributor.alternativeYACHIKU, Sunaoen
dc.contributor.alternativeOSANAI, Hiroakien
dc.contributor.alternativeYAMAUCHI, Kaoruen
dc.date.accessioned2010-06-01T01:55:39Z-
dc.date.available2010-06-01T01:55:39Z-
dc.date.issued1989-04-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/116484-
dc.description.abstract前立腺摘除術を受けた20症例にSBT/CPZを2 g投与し, 1時間後に血清および前立腺組織内について同一の条件下で採取し, SBT, CPZ濃度を測定した.1)血清濃度はCPZの方がSBTより有意に(p<0.01)高値に維持されていた.2)前立腺組織内濃度はCPZの方がSBTより有意に(p<0.05)高かった.3)前立腺組織内移行性は2剤間で異なり, 対血清比はSBTの方がCPZより有意に(p<0.05)高かったja
dc.description.abstractDiffusion of sulperazone (SBT) and cefoperazone (CPZ) into the prostatic tissue was studied in 20 cases. Two g of SBT/CPZ was injected intravenously and 1 hour later, prostatic tissue was obtained surgically and venous blood was drawn simultaneously. The serum concentration of CPZ (58.0 micrograms/ml +9.2) was higher than that of SBT (25.9 micrograms/ml +/- 9.3) and the prostatic tissue concentration of CPZ (14.9 micrograms/ml +/- 6.1) was higher than that of SBT (10.9 micrograms +/- 6.1). However, the SBT concentration ratio of prostatic tissue to serum level (P/S ratio) was significantly higher (42.5%) than that of CPZ (25.9%). The SBT concentration in the prostatic tissue was high enough to enhance the antibacterial activity of CPZ. SBT/CPZ was appraised to be an effective chemotherapeutic agent for infections of prostate caused by susceptible organisms, especially by beta-lactamase producing bacteria.en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher泌尿器科紀要刊行会ja
dc.subjectSulbactamen
dc.subjectCefoperazonen
dc.subjectProstatic iisue concentrationen
dc.subject.ndc494.9-
dc.titleSulbactam (SBT)とCefoperazon (CPZ)の前立腺組織内への移行についてja
dc.title.alternativeDiffusion of sulbactam and cefoperazone into the prostatic tissueen
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume35-
dc.identifier.issue4-
dc.identifier.spage727-
dc.identifier.epage734-
dc.textversionpublisher-
dc.sortkey30-
dc.address旭川医科大学泌尿器科学教室ja
dc.address旭川医科大学泌尿器科学教室ja
dc.address旭川医科大学泌尿器科学教室ja
dc.address旭川医科大学泌尿器科学教室ja
dc.address旭川医科大学泌尿器科学教室ja
dc.address旭川医科大学泌尿器科学教室ja
dc.address富良野協会病院泌尿器科ja
dc.address深川市立総合病院泌尿器科ja
dc.address.alternativethe Department of Urology, Asahikawa Medical Collegeen
dc.address.alternativethe Department of Urology, Asahikawa Medical Collegeen
dc.address.alternativethe Department of Urology, Asahikawa Medical Collegeen
dc.address.alternativethe Department of Urology, Asahikawa Medical Collegeen
dc.address.alternativethe Department of Urology, Asahikawa Medical Collegeen
dc.address.alternativethe Department of Urology, Asahikawa Medical Collegeen
dc.address.alternativethe Department of Urology, Furano Kyoukai Hospitalen
dc.address.alternativethe Department of Urology, Fukagawa City Hospitalen
dc.identifier.pmid2735275-
dcterms.accessRightsopen access-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
出現コレクション:Vol.35 No.4

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