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DCフィールド | 値 | 言語 |
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dc.contributor.author | 岡村, 廉晴 | ja |
dc.contributor.author | 橋本, 博 | ja |
dc.contributor.author | 森川, 満 | ja |
dc.contributor.author | 西原, 正幸 | ja |
dc.contributor.author | 佐賀, 祐司 | ja |
dc.contributor.author | 八竹, 直 | ja |
dc.contributor.author | 小山内, 裕昭 | ja |
dc.contributor.author | 山内, 薫 | ja |
dc.contributor.alternative | OKAMURA, Kiyoharu | en |
dc.contributor.alternative | HASHIMOTO, Hiroshi | en |
dc.contributor.alternative | MORIKAWA, Mitsuru | en |
dc.contributor.alternative | NISHIHARA, Masayuki | en |
dc.contributor.alternative | SAGA, Yuji | en |
dc.contributor.alternative | YACHIKU, Sunao | en |
dc.contributor.alternative | OSANAI, Hiroaki | en |
dc.contributor.alternative | YAMAUCHI, Kaoru | en |
dc.date.accessioned | 2010-06-01T01:55:39Z | - |
dc.date.available | 2010-06-01T01:55:39Z | - |
dc.date.issued | 1989-04 | - |
dc.identifier.issn | 0018-1994 | - |
dc.identifier.uri | http://hdl.handle.net/2433/116484 | - |
dc.description.abstract | 前立腺摘除術を受けた20症例にSBT/CPZを2 g投与し, 1時間後に血清および前立腺組織内について同一の条件下で採取し, SBT, CPZ濃度を測定した.1)血清濃度はCPZの方がSBTより有意に(p<0.01)高値に維持されていた.2)前立腺組織内濃度はCPZの方がSBTより有意に(p<0.05)高かった.3)前立腺組織内移行性は2剤間で異なり, 対血清比はSBTの方がCPZより有意に(p<0.05)高かった | ja |
dc.description.abstract | Diffusion of sulperazone (SBT) and cefoperazone (CPZ) into the prostatic tissue was studied in 20 cases. Two g of SBT/CPZ was injected intravenously and 1 hour later, prostatic tissue was obtained surgically and venous blood was drawn simultaneously. The serum concentration of CPZ (58.0 micrograms/ml +9.2) was higher than that of SBT (25.9 micrograms/ml +/- 9.3) and the prostatic tissue concentration of CPZ (14.9 micrograms/ml +/- 6.1) was higher than that of SBT (10.9 micrograms +/- 6.1). However, the SBT concentration ratio of prostatic tissue to serum level (P/S ratio) was significantly higher (42.5%) than that of CPZ (25.9%). The SBT concentration in the prostatic tissue was high enough to enhance the antibacterial activity of CPZ. SBT/CPZ was appraised to be an effective chemotherapeutic agent for infections of prostate caused by susceptible organisms, especially by beta-lactamase producing bacteria. | en |
dc.format.mimetype | application/pdf | - |
dc.language.iso | jpn | - |
dc.publisher | 泌尿器科紀要刊行会 | ja |
dc.subject | Sulbactam | en |
dc.subject | Cefoperazon | en |
dc.subject | Prostatic iisue concentration | en |
dc.subject.ndc | 494.9 | - |
dc.title | Sulbactam (SBT)とCefoperazon (CPZ)の前立腺組織内への移行について | ja |
dc.title.alternative | Diffusion of sulbactam and cefoperazone into the prostatic tissue | en |
dc.type | departmental bulletin paper | - |
dc.type.niitype | Departmental Bulletin Paper | - |
dc.identifier.ncid | AN00208315 | - |
dc.identifier.jtitle | 泌尿器科紀要 | ja |
dc.identifier.volume | 35 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 727 | - |
dc.identifier.epage | 734 | - |
dc.textversion | publisher | - |
dc.sortkey | 30 | - |
dc.address | 旭川医科大学泌尿器科学教室 | ja |
dc.address | 旭川医科大学泌尿器科学教室 | ja |
dc.address | 旭川医科大学泌尿器科学教室 | ja |
dc.address | 旭川医科大学泌尿器科学教室 | ja |
dc.address | 旭川医科大学泌尿器科学教室 | ja |
dc.address | 旭川医科大学泌尿器科学教室 | ja |
dc.address | 富良野協会病院泌尿器科 | ja |
dc.address | 深川市立総合病院泌尿器科 | ja |
dc.address.alternative | the Department of Urology, Asahikawa Medical College | en |
dc.address.alternative | the Department of Urology, Asahikawa Medical College | en |
dc.address.alternative | the Department of Urology, Asahikawa Medical College | en |
dc.address.alternative | the Department of Urology, Asahikawa Medical College | en |
dc.address.alternative | the Department of Urology, Asahikawa Medical College | en |
dc.address.alternative | the Department of Urology, Asahikawa Medical College | en |
dc.address.alternative | the Department of Urology, Furano Kyoukai Hospital | en |
dc.address.alternative | the Department of Urology, Fukagawa City Hospital | en |
dc.identifier.pmid | 2735275 | - |
dcterms.accessRights | open access | - |
dc.identifier.pissn | 0018-1994 | - |
dc.identifier.jtitle-alternative | Acta urologica Japonica | la |
dc.identifier.jtitle-alternative | Hinyokika Kiyo | en |
出現コレクション: | Vol.35 No.4 |
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