脊髄損傷患者に発生した膀胱憩室内腫瘍の1例

Abstract

A case of primary cancer of the vesical diverticulum in a patient with spinal cord injury is reported. A 78-year-old man with L1 incomplete paraplegia, who complained of asymptomatic gross hematuria, was referred to our hospital on September 2, 1986. Urethrocystoscopy showed papillary tumor in the diverticulum and three small stones. Histopathological findings of the biopsied specimen of the tumor revealed transitional cell carcinoma grade 3. Partial resection of the bladder involving diverticulum with right ureterovesiconeostomy and right pelvic lymphadenectomy was performed on October 17, 1986. Histopathological findings revealed transitional cell carcinoma grade 3 with submucosal invasion into the muscular layer (pT3bINF beta, ly2, V (+]. Two courses of combination chemotherapy with cyclophosphamide, adriamycin and cisplatin were given as a postoperative adjuvant chemotherapy, however he died of pneumonia on January 2, 1987. There have been reported 11 cases of a vesical neoplasm in patients with spinal cord injury in Japan.