尿中分離菌の年次的変遷とその薬剤感受性

Abstract

1983～1987年, 愛知医大泌尿器科受診患者を対象とした.外来由来株5, 725株の内訳はS. epidermidis (S.e.)(23.8%), Enterococcus sp. (E.s.)(16.5%), E. coil (E.c)(14.7%), Streptococcus sp. (S.s.)(12.6%), Proteus sp. (P.s.)(5.3%)の順であった.特に年次的変化は認められなかった.入院由来株4, 748株では, E.s. (23.1%), S.e. (18.7%), 真菌(12.9%), P. aeruginosa (P.a.)(8.0%), 他のグラム陰性桿菌(GNR)(6.8%)の順であった.年次的変化としてはS.s.の減少とS. aureusの増加, P.s., P.a.の減少, E.c.の増加が認められた.分離菌の感受性としてStaphylococcusはminocycline (MINO)に, E.s.はampicillin, MINOに良好な感受性を示し, E.c.は検討したがすべての抗生物質に良好な感受性を示した.P.a.はNorfloxacinとgentamycin以外は耐性を示す株が多かった

Statistical studies were performed on bacterial strains isolated from the urine of patients with various urological disease in our Urological Department between January, 1983 and December, 1987. In 1987, sensitivity tests of antibiotics to various pathogens were carried out. From the outpatients, 5, 725 bacterial strains were isolated. S. epidermidis was isolated most frequently (23.8%), followed by Enterococcus species (16.5%), E. coli (14.7%), Streptococcus species (12.6%), Proteus species (5.3%), other GNR (4.6%), P, aeruginosa (4.5%), Klebsiella species (4.4%), and others. From the inpatients, 4, 747 bacterial strains were isolated. Enterococcus species was isolated most frequently (23.1%), followed by S. epidermidis (18.7%), Fungi (12.9%), P. aeruginosa (8.0%), other GNR (6.8%), Streptococcus species (5.4%), Enterobacter species (4.8%), E. coli (4.1%), S. aureus (4.1%) and others. Annual change of distribution of organisms indicated that S. aureus from outpatients had a tendency to increase and Streptococcus species had a tendency to decrease. Whereas from inpatients, E. coli, other GNR, Pseudomonas species and Enterobacter species had a tendency to increase, and Streptococcus species, P. aeruginosa, Proteus species and Klebsiella species had a tendency to decrease. S. epidermidis showed a high sensitivity to minocycline and cephalothin, and Enterococcus showed a high sensitivity to ampicillin and minocycline, but did not show good sensitivity to cefoperazone and latamoxef. E. coli showed a high sensitivity to all drug we tested. P. aeruginosa showed a high sensitivity to gentamycin and norflaxacin, but did not show good sensitivity to other many drugs we tested.