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このアイテムのファイル:
| ファイル | 記述 | サイズ | フォーマット | |
|---|---|---|---|---|
| 35_1323.pdf | 335.7 kB | Adobe PDF | 見る/開く |
| タイトル: | 浸潤性膀胱癌およびリンパ節転移を有する膀胱癌に対するM-VAC療法の治療成績 |
| その他のタイトル: | M-VAC chemotherapy for patients with lymph node metastases and/or locally advanced bladder carcinoma |
| 著者: | 井川, 幹夫  植木, 哲裕 上田, 光孝 岡田, 克彦 碓井, 亜 大西, 喜夫 久米, 隆 桝, 知果夫 石野, 外志勝 中津, 博 児玉, 光人 北野, 太路 鵜飼, 麟三 藤井, 元広 広本, 宣彦 中野, 博 田戸, 治 畑地, 康助 松木, 暁 小野, 浩 平山, 多秋 福重, 満 白石, 恒雄 |
| 著者名の別形: | Igawa, Mikio Ueki, Tetsuhiro Ueda, Mitsutaka Okada, Katsuhiko Usui, Tsuguru Ohnishi, Yoshio Kume, Takashi Masu, Chikao Ishino, Toshikatsu Nakatsu, Hiroshi Kodama, Mitsuto Kitano, Taiji Ukai, Rinzo Fujii, Motohiro Hiromoto, Nobuyuki Nakano, Hiroshi Tado, Osamu Hatachi, Kousuke Matsuki, Satoru Ono, Hiroshi Hirayama, Masaaki Fukushige, Mitsuru Shiraishi, Tsuneo |
| キーワード: | Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols/adverse effects/therapeutic use Carcinoma, Transitional Cell/drug therapy/mortality/pathology Cisplatin/administration & dosage Doxorubicin/administration & dosage Female Humans Lymphatic Metastasis Male Methotrexate/administration & dosage Middle Aged Multicenter Studies as Topic Survival Rate Urinary Bladder Neoplasms/drug therapy/mortality/pathology Vinblastine/administration & dosage |
| 発行日: | Aug-1989 |
| 出版者: | 泌尿器科紀要刊行会 |
| 誌名: | 泌尿器科紀要 |
| 巻: | 35 |
| 号: | 8 |
| 開始ページ: | 1323 |
| 終了ページ: | 1327 |
| 抄録: | Sixteen patients with lymph nodes metastases and/or locally advanced bladder carcinoma were treated with a combination chemotherapy regimen consisting of methotrexate, vinblastine, adriamycin, and cisplatin (M-VAC) from November 1986 through September 1988. There were 14 men and 2 women. The median age was 61.9 years, with a range from 43 to 81 years. Complete response (CR) was observed in 6 of 16 patients (38%), partial response (PR) was confirmed in 5 of 16 patients (31%), and overall response rate was 69%. Median duration of response was 10.3 and 5.2 months in CR and PR patients, respectively. The myelosuppression with this regimen was tolerable. This study demonstrates that the M-VAC regimen is effective in the invasive bladder carcinoma with or without lymph nodes metastases. However, the duration of response is relatively short, and the true long-term benefits of this regimen remain to be determined. |
| URI: | http://hdl.handle.net/2433/116644 |
| PubMed ID: | 2683648 |
| 出現コレクション: | Vol.35 No.8 |
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