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36_465.pdf | 2.49 MB | Adobe PDF | 見る/開く |
タイトル: | 多剤併用化学内分泌療法が有効な若年性進行前立腺癌の1例 |
その他のタイトル: | A case of advanced prostatic cancer in a 44-year-old treated effectively with combination chemo-endocrine therapy |
著者: | 荒木, 亜人 楠山, 弘之 加藤, 幹雄 岡田, 耕市 |
著者名の別形: | Araki, Shigeto Kusuyama, Hiroyuki Kato, Mikio Okada, Koichi |
キーワード: | Prostatic cancer in young adults Poorly differentiated adenocarcinoma Chemo-endocrine therapy |
発行日: | Apr-1990 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 36 |
号: | 4 |
開始ページ: | 465 |
終了ページ: | 469 |
抄録: | In a 44-year-old man with persistent back-pain for 3 months duration, radiological and echological investigations revealed prostatic mass lesion with multiple osteoblastic involvements. Transrectal biopsy to the prostate demonstrated pathohistologically poorly differentiated adenocarcinoma (Gleason's score 4-4:8). Serum ACP, ALP and IAP were elevated at the initial diagnosis pathologically. The clinical and pathological stage was D2, without metastasis to lung and liver. Combination chemo-endocrine therapy (methotrexate, adriamycin, pepleomycin, Estracyt and tegafur) with bilateral orchiectomies was performed exclusively as initial treatment. These consecutive treatments brought remarkable reduction of the prostatic mass lesion, decrease of tumor markers to normal range, rapid improvement of subjective symptoms and distinct decrease of abnormal activity in bone scintigram. More than 3 years survival was obtained, and normal performance-status was kept. Prostatic cancer in middle-aged adults is reviewed and discussed. |
URI: | http://hdl.handle.net/2433/116875 |
PubMed ID: | 1696064 |
出現コレクション: | Vol.36 No.4 |
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