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タイトル: 多剤併用化学内分泌療法が有効な若年性進行前立腺癌の1例
その他のタイトル: A case of advanced prostatic cancer in a 44-year-old treated effectively with combination chemo-endocrine therapy
著者: 荒木, 亜人  KAKEN_name
楠山, 弘之  KAKEN_name
加藤, 幹雄  KAKEN_name
岡田, 耕市  KAKEN_name
著者名の別形: Araki, Shigeto
Kusuyama, Hiroyuki
Kato, Mikio
Okada, Koichi
キーワード: Prostatic cancer in young adults
Poorly differentiated adenocarcinoma
Chemo-endocrine therapy
発行日: Apr-1990
出版者: 泌尿器科紀要刊行会
誌名: 泌尿器科紀要
巻: 36
号: 4
開始ページ: 465
終了ページ: 469
抄録: In a 44-year-old man with persistent back-pain for 3 months duration, radiological and echological investigations revealed prostatic mass lesion with multiple osteoblastic involvements. Transrectal biopsy to the prostate demonstrated pathohistologically poorly differentiated adenocarcinoma (Gleason's score 4-4:8). Serum ACP, ALP and IAP were elevated at the initial diagnosis pathologically. The clinical and pathological stage was D2, without metastasis to lung and liver. Combination chemo-endocrine therapy (methotrexate, adriamycin, pepleomycin, Estracyt and tegafur) with bilateral orchiectomies was performed exclusively as initial treatment. These consecutive treatments brought remarkable reduction of the prostatic mass lesion, decrease of tumor markers to normal range, rapid improvement of subjective symptoms and distinct decrease of abnormal activity in bone scintigram. More than 3 years survival was obtained, and normal performance-status was kept. Prostatic cancer in middle-aged adults is reviewed and discussed.
URI: http://hdl.handle.net/2433/116875
PubMed ID: 1696064
出現コレクション:Vol.36 No.4

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