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タイトル: | 糖尿病性神経因性膀胱に対するGangliosideの効果について |
その他のタイトル: | The effect of ganglioside on diabetic neurogenic bladder |
著者: | 田中, 重人 森川, 洋二 安本, 亮二 |
著者名の別形: | Tanaka, Shigeto Morikawa, Yoji Yasumoto, Ryoji |
キーワード: | Aged Aged, 80 and over Diabetes Complications Drug Evaluation Female Gangliosides/administration & dosage/therapeutic use Humans Injections, Intramuscular Male Middle Aged Urinary Bladder, Neurogenic/drug therapy/etiology/physiopathology Urodynamics |
発行日: | Jun-1990 |
出版者: | 泌尿器科紀要刊行会 |
誌名: | 泌尿器科紀要 |
巻: | 36 |
号: | 6 |
開始ページ: | 661 |
終了ページ: | 666 |
抄録: | The effect of ganglioside was studied in 6 diabetic patients with neurogenic bladder. Ganglioside is glycosphingolipids which seems to be involved in the processes of nerve growth, regeneration and tissue reinnervation. The treatment consisted in the daily intramuscular administration of 20 mg ganglioside. Clinical symptoms, vibration sensation and urodynamic studies were recorded at the beginning and 4 weeks later. The clinical responses assessed by subjective complaints and vibration sensation were effective, but no statistically significant difference in urodynamic studies was obtained. Side effects were not observed. In conclusion, ganglioside treatment seems to have a positive effect on diabetic neurogenic bladder. |
URI: | http://hdl.handle.net/2433/116930 |
PubMed ID: | 2239557 |
出現コレクション: | Vol.36 No.6 |
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