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タイトル: 糖尿病性神経因性膀胱に対するGangliosideの効果について
その他のタイトル: The effect of ganglioside on diabetic neurogenic bladder
著者: 田中, 重人  KAKEN_name
森川, 洋二  KAKEN_name
安本, 亮二  KAKEN_name
著者名の別形: Tanaka, Shigeto
Morikawa, Yoji
Yasumoto, Ryoji
キーワード: Aged
Aged, 80 and over
Diabetes Complications
Drug Evaluation
Female
Gangliosides/administration & dosage/therapeutic use
Humans
Injections, Intramuscular
Male
Middle Aged
Urinary Bladder, Neurogenic/drug therapy/etiology/physiopathology
Urodynamics
発行日: Jun-1990
出版者: 泌尿器科紀要刊行会
誌名: 泌尿器科紀要
巻: 36
号: 6
開始ページ: 661
終了ページ: 666
抄録: The effect of ganglioside was studied in 6 diabetic patients with neurogenic bladder. Ganglioside is glycosphingolipids which seems to be involved in the processes of nerve growth, regeneration and tissue reinnervation. The treatment consisted in the daily intramuscular administration of 20 mg ganglioside. Clinical symptoms, vibration sensation and urodynamic studies were recorded at the beginning and 4 weeks later. The clinical responses assessed by subjective complaints and vibration sensation were effective, but no statistically significant difference in urodynamic studies was obtained. Side effects were not observed. In conclusion, ganglioside treatment seems to have a positive effect on diabetic neurogenic bladder.
URI: http://hdl.handle.net/2433/116930
PubMed ID: 2239557
出現コレクション:Vol.36 No.6

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