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dc.contributor.author名出, 頼男ja
dc.contributor.author熊本, 悦明ja
dc.contributor.author広瀬, 崇興ja
dc.contributor.author土田, 正義ja
dc.contributor.author折笠, 精一ja
dc.contributor.author阿曽, 佳郎ja
dc.contributor.author押, 正也ja
dc.contributor.author町田, 豊平ja
dc.contributor.author鈴木, 恵三ja
dc.contributor.author河田, 幸道ja
dc.contributor.author坂, 義人ja
dc.contributor.author岡田, 謙一郎ja
dc.contributor.author守殿, 貞夫ja
dc.contributor.author荒川, 創一ja
dc.contributor.author大森, 弘之ja
dc.contributor.author公文, 裕巳ja
dc.contributor.author仁平, 寛巳ja
dc.contributor.author香川, 征ja
dc.contributor.author熊澤, 淨一ja
dc.contributor.author松本, 哲朗ja
dc.contributor.author江藤, 耕作ja
dc.contributor.author大井, 好忠ja
dc.contributor.author上野, 一恵ja
dc.contributor.author小川, 暢也ja
dc.contributor.alternativeNaide, Yorioen
dc.contributor.alternativeKumamoto, Yoshiakien
dc.contributor.alternativeHirose, Takaokien
dc.contributor.alternativeTsuchida, Seigien
dc.contributor.alternativeOrikasa, Seiichien
dc.contributor.alternativeAso, Yoshiroen
dc.contributor.alternativeOshi, Masayaen
dc.contributor.alternativeMachida, Toyoheien
dc.contributor.alternativeSuzuki, Keizoen
dc.contributor.alternativeKawada, Yukimichien
dc.contributor.alternativeBan, Yoshihitoen
dc.contributor.alternativeOkada, Kenichiroen
dc.contributor.alternativeKamidono, Sadaoen
dc.contributor.alternativeArakawa, Soichien
dc.contributor.alternativeOomori, Hiroyukien
dc.contributor.alternativeKumon, Hiromien
dc.contributor.alternativeNihira, Hiromien
dc.contributor.alternativeKagawa, Susumuen
dc.contributor.alternativeKumazawa, Joichien
dc.contributor.alternativeMatsumoto, Tetsuroen
dc.contributor.alternativeEto, Kosakuen
dc.contributor.alternativeOhi, Yoshitadaen
dc.contributor.alternativeUeno, Kazueen
dc.contributor.alternativeOgawa, Nobuyaen
dc.date.accessioned2010-06-01T02:24:36Z-
dc.date.available2010-06-01T02:24:36Z-
dc.date.issued1991-04-
dc.identifier.issn0018-1994-
dc.identifier.urihttp://hdl.handle.net/2433/117148-
dc.description.abstractCPRは1回0.5 gまたは1.0 gを, CAZは1回1.0 gを1日2回, 点滴静注により5日間連続投与し, 臨床効果はUTI薬効評価基準により評価した.総投与症例530例中効果判定が可能であった症例はCPR 1日1 g投与群141例, CPR 1日2 g投与群136例, CAZ 1日2 g投与群140例であった.CPRは複雑性尿路感染症に対してCAZと同様に有用性の高い薬剤であるja
dc.description.abstractWe carried out a randomized multi-center study comparing cefpirome (CPR) 0.5 g b.i.d. (1 g group), 1.0 g b.i.d. (2 g group) and ceftazidime (CAZ) 1.0 g b.i.d. (CAZ group) in the treatment of complicated urinary tract infections. Patients who were over 16 years old and had underlying urinary tract disease, with bacteriuria of more than 10(4) cells ml or more and pyuria of more than 5 WBCs/hpf (x 400) or more were randomly allocated to receive either 0.5 g of CPR, 1.0 g of CPR or 1.0 g of CAZ twice a day for 5 days by intravenous drip infusion. The overall clinical efficacy of the treatment was evaluated by the criteria of the Japanese UTI Committee as excellent, moderate or poor, on the basis of the changes in pyuria and bacteriuria. A total of 530 patients were treated. Of these, 141 patients in the 1 g group, 136 in the 2 g group, and 140 in the CAZ group were evaluable for clinical efficacy. No significant differences in background characteristics were observed among the treatment groups. The overall clinical efficacy rate of the 1 g group, the 2 g group and the CAZ group was 80.1%, 76.5% and 71.4%, respectively. The differences were not statistically significant. The overall bacteriological eradication rate of the 1 g group, the 2 g group and the CAZ group was 81.0%, 88.1% and 83.8%. The differences were not statistically significant either. Against the enterococcus group, however, eradication rates were higher significantly in the 1 g and 2 g groups than in the CAZ group. The incidence of adverse reactions was 2.2% in the 1 g group, 0.6% in the 2 g group and 2.9% in the CAZ group. Abnormal laboratory data after medication were observed in 10.8% of the 1 g group, 12.1% of the 2 g group and 10.2% of the CAZ group, the difference not being statistically significant. There were no serious untoward reactions to medication. From the results obtained in this study, we consider that CPR is at least as useful as CAZ in the treatment of complicated urinary tract infections.en
dc.format.mimetypeapplication/pdf-
dc.language.isojpn-
dc.publisher泌尿器科紀要刊行会ja
dc.subjectCefpiromeen
dc.subjectComplicated UTIen
dc.subjectComparative studyen
dc.subject.ndc494.9-
dc.title複雑性尿路感染症に対するCefpirome(CPR)とCeftazidime(CAZ)の比較検討ja
dc.title.alternativeComparative study of cefpirome and ceftazidime in complicated urinary tract infectionsen
dc.typedepartmental bulletin paper-
dc.type.niitypeDepartmental Bulletin Paper-
dc.identifier.ncidAN00208315-
dc.identifier.jtitle泌尿器科紀要ja
dc.identifier.volume37-
dc.identifier.issue4-
dc.identifier.spage447-
dc.identifier.epage464-
dc.textversionpublisher-
dc.sortkey20-
dc.address藤田学園保健衛生大学医学部泌尿器科学教室ja
dc.address札幌医科大学泌尿器科学教室ja
dc.address札幌医科大学泌尿器科学教室ja
dc.address秋田大学医学部泌尿器科学教室ja
dc.address東北大学医学部泌尿器科学教室ja
dc.address東京大学医学部泌尿器科学教室ja
dc.address東京大学医学部泌尿器科学教室ja
dc.address東京慈恵会医科大学泌尿器科学教室ja
dc.address平塚市民病院泌尿器科ja
dc.address岐阜大学医学部泌尿器科学教室ja
dc.address岐阜大学医学部泌尿器科学教室ja
dc.address福井医科大学泌尿器科学教室ja
dc.address神戸大学医学部泌尿器科学教室ja
dc.address神戸大学医学部泌尿器科学教室ja
dc.address岡山大学医学部泌尿器科学教室ja
dc.address岡山大学医学部泌尿器科学教室ja
dc.address広島大学医学部泌尿器科学教室ja
dc.address徳島大学医学部泌尿器科学教室ja
dc.address九州大学医学部泌尿器科学教室ja
dc.address九州大学医学部泌尿器科学教室ja
dc.address久留米大学医学部泌尿器科学教室ja
dc.address鹿児島大学医学部泌尿器科学教室ja
dc.address岐阜大学医学部付属嫌気性菌実験施設ja
dc.address愛媛大学医学部薬理学教室ja
dc.address.alternativethe Department of Urology, Fujita- Gakuen Health University, School of Medicineen
dc.address.alternativethe Department of Urology, Sapporo Medical Collegeen
dc.address.alternativethe Department of Urology, Sapporo Medical Collegeen
dc.address.alternativethe Department of Urology, Akita University, School of Medicineen
dc.address.alternativethe Department of Urology, Tohoku University, School of Medicineen
dc.address.alternativethe Department of Urology, Faculty of Medicine, University of Tokyoen
dc.address.alternativethe Department of Urology, Faculty of Medicine, University of Tokyoen
dc.address.alternativethe Department of Urology, the Jikei University, School of Medicineen
dc.address.alternativethe Department of Urology, Hiratsuka Municipal Hospitalen
dc.address.alternativethe Department of Urology, Gifu University School of Medicineen
dc.address.alternativethe Department of Urology, Gifu University School of Medicineen
dc.address.alternativethe Department of Urology, Fukui Medical Schoolen
dc.address.alternativethe Department of Urology, Kobe University School of Medicineen
dc.address.alternativethe Department of Urology, Kobe University School of Medicineen
dc.address.alternativethe Department of Urology, Okayama University, Medical Schoolen
dc.address.alternativethe Department of Urology, Okayama University, Medical Schoolen
dc.address.alternativethe Department of Urology, Hiroshima University Medical Schoolen
dc.address.alternativethe Department of Urology, School of Medicine, the University of Tokushimaen
dc.address.alternativethe Department of Urology, Faculty of Medicine, Kyushu Universityen
dc.address.alternativethe Department of Urology, Faculty of Medicine, Kyushu Universityen
dc.address.alternativethe Department of Urology, Kurume University, School of Medicineen
dc.address.alternativethe Department of Urology, Faculty of Medicine, Kagoshima Universityen
dc.address.alternativethe Institute of Anaerobic Bacteriology, Gifu University School of Medicineen
dc.address.alternativethe Department of Pharmacology, Ehime University School of Medicineen
dc.identifier.pmid1892004-
dcterms.accessRightsopen access-
dc.identifier.pissn0018-1994-
dc.identifier.jtitle-alternativeActa urologica Japonicala
dc.identifier.jtitle-alternativeHinyokika Kiyoen
出現コレクション:Vol.37 No.4

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